Expression of Coagulation Factor VII (F7)

Stable Identifier
R-MMU-549502
Type
Reaction [omitted]
Species
Mus musculus
Compartment
ReviewStatus
5/5
General
SVG |   | PPTX  | SBGN
Expression of Coagulation Factor VII (F7)
The Factor VII (F7) gene is transcribed to yield mRNA and the mRNA is translated to yield protein. The promoter of the F7 gene contains an E-box which binds the Bmal1:Clock (Arntl:Clock) heterodimer and the Bmal1:Npas2 (Arntl:Npas2) heterodimer, conferring circadian expression on Factor VII mRNA and protein.
Literature References
PubMed ID Title Journal Year
18316400 Evidence for an overlapping role of CLOCK and NPAS2 transcription factors in liver circadian oscillators

FoĆ”, A, Tosini, G, Caruso, P, Cavallari, N, Bertolucci, C, Bernardi, F, Colognesi, I, Pinotti, M, Aguzzi, J, Chen, Z

Mol Cell Biol 2008
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Orthologous Events
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