Reactome | Mrps18a [mitochondrial inner membrane]

Mrps18a [mitochondrial inner membrane]

Stable Identifier

R-MMU-5368200

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

mitochondrial inner membrane

Synonyms

MRPS18A, Q99N85

Locations in the PathwayBrowser

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Metabolism of proteins (Mus musculus)

- Translation (Mus musculus)
  - Mitochondrial translation (Mus musculus)
    - Mitochondrial translation elongation (Mus musculus)
      - 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP (Mus musculus)
        
        55S ribosome:mRNA:tRNA:peptidyl-tRNA at A-site [mitochondrial inner membrane] (Mus musculus)
        
        55S ribosome [mitochondrial inner membrane] (Mus musculus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Mus musculus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Mus musculus)
        
        Mrps18a [mitochondrial inner membrane] (Mus musculus)
        
        55S ribosome:mRNA:tRNA:peptidyl-tRNA:GFM1:GTP [mitochondrial inner membrane] (Mus musculus)
        
        55S ribosome [mitochondrial inner membrane] (Mus musculus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Mus musculus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Mus musculus)
        
        Mrps18a [mitochondrial inner membrane] (Mus musculus)
    - Mitochondrial translation termination (Mus musculus)
      - 55S ribosome hydrolyzes peptidyl-tRNA bond and MTRF1L hydrolyzes GTP (Mus musculus)
        
        55S ribosome:mRNA:peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Mus musculus)
        
        55S ribosome [mitochondrial inner membrane] (Mus musculus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Mus musculus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Mus musculus)
        
        Mrps18a [mitochondrial inner membrane] (Mus musculus)
        
        55S ribosome:mRNA:tRNA [mitochondrial inner membrane] (Mus musculus)
        
        55S ribosome [mitochondrial inner membrane] (Mus musculus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Mus musculus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Mus musculus)
        
        Mrps18a [mitochondrial inner membrane] (Mus musculus)
      - Hydrolysis of GTP and dissociation of 28S and 39S subunits (Mus musculus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Mus musculus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Mus musculus)
        
        Mrps18a [mitochondrial inner membrane] (Mus musculus)
        
        55S ribosome:MRRF:GFM2:GTP [mitochondrial inner membrane] (Mus musculus)
        
        55S ribosome [mitochondrial inner membrane] (Mus musculus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Mus musculus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Mus musculus)
        
        Mrps18a [mitochondrial inner membrane] (Mus musculus)
      - MRRF binds 55S ribosome:mRNA:tRNA (Mus musculus)
        
        55S ribosome:mRNA:tRNA [mitochondrial inner membrane] (Mus musculus)
        
        55S ribosome [mitochondrial inner membrane] (Mus musculus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Mus musculus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Mus musculus)
        
        Mrps18a [mitochondrial inner membrane] (Mus musculus)
        
        55S ribosome:mRNA:tRNA:MRRF [mitochondrial inner membrane] (Mus musculus)
        
        55S ribosome [mitochondrial inner membrane] (Mus musculus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Mus musculus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Mus musculus)
        
        Mrps18a [mitochondrial inner membrane] (Mus musculus)
      - MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA (Mus musculus)
        
        55S ribosome:mRNA:peptidyl-tRNA at P-site [mitochondrial inner membrane] (Mus musculus)
        
        55S ribosome [mitochondrial inner membrane] (Mus musculus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Mus musculus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Mus musculus)
        
        Mrps18a [mitochondrial inner membrane] (Mus musculus)
        
        55S ribosome:mRNA:peptidyl-tRNA:MTRF1L:GTP [mitochondrial inner membrane] (Mus musculus)
        
        55S ribosome [mitochondrial inner membrane] (Mus musculus)
        
        28S ribosomal subunit [mitochondrial inner membrane] (Mus musculus)
        
        MRPS18A,B,C [mitochondrial inner membrane] (Mus musculus)
        
        Mrps18a [mitochondrial inner membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q99N85

Gene Names

Mrps18a

Reference Genes

BioGPS Gene:68565 Mrps18a

ENSEMBL:ENSMUSG00000023967

KEGG Gene (Mus musculus):68565 Mrps18a

Monarch:68565 Mrps18a

NCBI Gene:68565 Mrps18a

Reference Transcript

RefSeq:NM_026768.3 Mrps18a

Participates

as a member of

MRPS18A,B,C [mitochondrial inner membrane] (Mus musculus)

Inferred From

MRPS18A [mitochondrial inner membrane] (Homo sapiens)

Cross References

RefSeq

NP_081044.1

PRO

Q99N85

MGI

1915815