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CYP2E1 [endoplasmic reticulum membrane]
Stable Identifier
R-MMU-52681
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
endoplasmic reticulum membrane
Synonyms
Q05421
Locations in the PathwayBrowser
Expand all
Drug ADME (Mus musculus)
Aspirin ADME (Mus musculus)
CYP2,3 cytochromes hydroxylate ST to 2,3-DHBA (Mus musculus)
CYP2,3 cytochromes [endoplasmic reticulum membrane] (Mus musculus)
CYP2E1 [endoplasmic reticulum membrane] (Mus musculus)
CYP2,3 cytochromes hydroxylate ST to 2,5-DHBA (Mus musculus)
CYP2,3 cytochromes [endoplasmic reticulum membrane] (Mus musculus)
CYP2E1 [endoplasmic reticulum membrane] (Mus musculus)
Paracetamol ADME (Mus musculus)
CYP2E1 monooxygenates APAP to NAPQI (Mus musculus)
CYP2E1 [endoplasmic reticulum membrane] (Mus musculus)
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase I - Functionalization of compounds (Mus musculus)
Cytochrome P450 - arranged by substrate type (Mus musculus)
Xenobiotics (Mus musculus)
CYP2C19 5-hydroxylates omeprazole (Mus musculus)
Cytochrome P450 (CYP2C8 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2E1 [endoplasmic reticulum membrane] (Mus musculus)
CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation (Mus musculus)
Cytochrome P450 (CYP2C8 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2E1 [endoplasmic reticulum membrane] (Mus musculus)
CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation (Mus musculus)
Cytochrome P450 (CYP2C9 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2E1 [endoplasmic reticulum membrane] (Mus musculus)
CYP2D6 4-hydroxylates debrisoquine (Mus musculus)
Cytochrome P450 (CYP2D6 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2E1 [endoplasmic reticulum membrane] (Mus musculus)
CYP2E1 reactions (Mus musculus)
Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI) (Mus musculus)
Cytochrome P450 (CYP2E1 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2E1 [endoplasmic reticulum membrane] (Mus musculus)
Benzene is hydroxylated to phenol (Mus musculus)
Cytochrome P450 (CYP2E1 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2E1 [endoplasmic reticulum membrane] (Mus musculus)
Dehalogenation of carbon tetrachloride to form a free radical (Mus musculus)
Cytochrome P450 (CYP2E1 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2E1 [endoplasmic reticulum membrane] (Mus musculus)
Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide (Mus musculus)
Cytochrome P450 (CYP2E1 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2E1 [endoplasmic reticulum membrane] (Mus musculus)
MEOS oxidizes ethanol to acetaldehyde (Mus musculus)
Cytochrome P450 (CYP2E1 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2E1 [endoplasmic reticulum membrane] (Mus musculus)
Vinyl chloride is oxidized to 2-Chloroethylene oxide (Mus musculus)
Cytochrome P450 (CYP2E1 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2E1 [endoplasmic reticulum membrane] (Mus musculus)
CYP2F1 dehydrogenates 3-methylindole (Mus musculus)
Cytochrome P450 (CYP2F1 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2E1 [endoplasmic reticulum membrane] (Mus musculus)
Coumarin is 7-hydroxylated by CYP2A13 (Mus musculus)
Cytochrome P450 (CYP2A13 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2E1 [endoplasmic reticulum membrane] (Mus musculus)
Coumarin is 7-hydroxylated by CYP2A6 (Mus musculus)
Cytochrome P450 (CYP2A3 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2E1 [endoplasmic reticulum membrane] (Mus musculus)
Cyclophosphamide is 4-hydroxylated by CYP2B6 (Mus musculus)
Cytochrome P450 (CYP2B6 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2E1 [endoplasmic reticulum membrane] (Mus musculus)
O-atom dealkylation of dextromethorphan (Mus musculus)
Cytochrome P450 (CYP2D6 based) [endoplasmic reticulum membrane] (Mus musculus)
CYP2E1 [endoplasmic reticulum membrane] (Mus musculus)
Metabolism of lipids (Mus musculus)
Biosynthesis of specialized proresolving mediators (SPMs) (Mus musculus)
Biosynthesis of DHA-derived SPMs (Mus musculus)
Biosynthesis of maresins (Mus musculus)
Biosynthesis of maresin-like SPMs (Mus musculus)
CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA (Mus musculus)
CYP2E1 [endoplasmic reticulum membrane] (Mus musculus)
CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA (Mus musculus)
CYP2E1 [endoplasmic reticulum membrane] (Mus musculus)
CYPs hydroxylate DHA to 14(R)-HDHA (Mus musculus)
CYP1A2,2C8,2C9,2D6,2E1,3A4 [endoplasmic reticulum membrane] (Mus musculus)
CYP2E1 [endoplasmic reticulum membrane] (Mus musculus)
External Reference Information
External Reference
UniProt:Q05421
Reference Genes
BioGPS Gene:13106
ENSEMBL:ENSMUSG00000025479
ENSEMBL:ENSMUSG00000025479.10
KEGG Gene (Mus musculus):13106
Monarch:13106
NCBI Gene:13106
UCSC:Q05421
Reference Transcript
RefSeq:NM_021282.2
Other Identifiers
10558673
13106
1415994_at
17484587
4311055
4568357
4618728
4624914
4762372
4780542
4909450
5000510
5096737
5263914
5328457
5425945
5482378
5542302
93996_at
A_51_P283456
A_55_P1966690
A_55_P1999301
GE38104
GO:0000139
GO:0001676
GO:0002933
GO:0003824
GO:0004497
GO:0005506
GO:0005737
GO:0005739
GO:0005743
GO:0005783
GO:0005789
GO:0005794
GO:0006629
GO:0006631
GO:0006641
GO:0006805
GO:0008202
GO:0008392
GO:0009617
GO:0016020
GO:0016098
GO:0016491
GO:0016705
GO:0016712
GO:0018601
GO:0018960
GO:0019373
GO:0019899
GO:0020037
GO:0030544
GO:0043226
GO:0043231
GO:0046483
GO:0046872
GO:0051879
GO:0070330
GO:0120319
ILMN_1214390
ILMN_2687014
m30844_s_at
mMC011431
Participates
as a member of
CYP1A2,2C8,2C9,2D6,2E1,3A4 [endoplasmic reticulum membrane] (Mus musculus)
CYP2,3 cytochromes [endoplasmic reticulum membrane] (Mus musculus)
Cytochrome P450 (CYP2E1 based) [endoplasmic reticulum membrane] (Mus musculus)
as a candidate of
Cytochrome P450 (CYP2C9 based) [endoplasmic reticulum membrane] (Mus musculus)
Cytochrome P450 (CYP2B6 based) [endoplasmic reticulum membrane] (Mus musculus)
Cytochrome P450 (CYP2A13 based) [endoplasmic reticulum membrane] (Mus musculus)
Cytochrome P450 (CYP2D6 based) [endoplasmic reticulum membrane] (Mus musculus)
Cytochrome P450 (CYP2F1 based) [endoplasmic reticulum membrane] (Mus musculus)
Cytochrome P450 (CYP2C8 based) [endoplasmic reticulum membrane] (Mus musculus)
Cytochrome P450 (CYP2A3 based) [endoplasmic reticulum membrane] (Mus musculus)
Inferred From
CYP2E1 [endoplasmic reticulum membrane]
(Homo sapiens)
Cross References
RefSeq
NP_067257.1
IntEnz
1.14.13.n7
Ensembl
ENSMUST00000026552
,
ENSMUSP00000026552
,
ENSMUSG00000025479
PRO
Q05421
MGI
88607
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