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NCAM1 interacts with T- and L-type VDCC
Stable Identifier
R-MMU-525831
Type
Reaction [binding]
Species
Mus musculus
Compartment
plasma membrane
ReviewStatus
5/5
General
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Level 2
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NCAM1 associates with T- and L-type voltage-dependent Ca+2 channels (VDCC) in growthcones at the sites of NCAM1 clustering. This interaction leads to the NCAM-dependent Ca+2 influx to the cell.
Literature References
PubMed ID
Title
Journal
Year
18809727
NCAM induces CaMKIIalpha-mediated RPTPalpha phosphorylation to enhance its catalytic activity and neurite outgrowth
Leshchyns'ka, I
,
Bodrikov, V
,
Sytnyk, V
,
den Hertog, J
,
Schachner, M
J Cell Biol
2008
Participants
Input
Ncam1 [plasma membrane]
(Mus musculus)
T- and L-type VDCC [plasma membrane]
(Mus musculus)
Output
Ncam1:T- and L-type VDCC [plasma membrane]
(Mus musculus)
Orthologous Events
NCAM1 interacts with T- and L-type VDCC (Homo sapiens)
Authored
Garapati, P V (2009-05-30)
Reviewed
Walmod, PS (2009-05-26)
Maness, PF (2009-05-26)
Created
Garapati, P V (2010-02-22)
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