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What is Reactome ?
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XIAP [cytosol]
Stable Identifier
R-MMU-50849
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
Q60989
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Mus musculus)
Apoptosis (Mus musculus)
Intrinsic Pathway for Apoptosis (Mus musculus)
Apoptotic factor-mediated response (Mus musculus)
Cytochrome c-mediated apoptotic response (Mus musculus)
Activation of caspases through apoptosome-mediated cleavage (Mus musculus)
Cleavage of Procaspase-3 by the apoptosome (Mus musculus)
XIAP [cytosol] (Mus musculus)
Cleavage of Procaspase-7 by the apoptosome (Mus musculus)
XIAP [cytosol] (Mus musculus)
Formation of apoptosome (Mus musculus)
Regulation of the apoptosome activity (Mus musculus)
XIAP binds CASP9 (Mus musculus)
XIAP [cytosol] (Mus musculus)
XIAP:apoptosome [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
SMAC, XIAP-regulated apoptotic response (Mus musculus)
SEPT4 binds XIAP (Mus musculus)
SEPT4 dimer:XIAP [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
SMAC (DIABLO) binds to IAPs (Mus musculus)
SMAC (DIABLO) binds XIAP (Mus musculus)
DIABLO dimer:XIAP [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
SMAC binds XIAP:Caspase-7 (Mus musculus)
DIABLO:XIAP:Caspase-7 [cytosol] (Mus musculus)
XIAP:Caspase-7 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
XIAP:Caspase-7 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes (Mus musculus)
Dissociation of Caspase-7 from DIABLO:XIAP:Caspase-7 (Mus musculus)
DIABLO dimer:XIAP [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
DIABLO:XIAP:Caspase-7 [cytosol] (Mus musculus)
XIAP:Caspase-7 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
XIAP binds CASP3 (Mus musculus)
DIABLO:XIAP:Caspase-3 [cytosol] (Mus musculus)
XIAP:Caspase-3 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
XIAP:Caspase-3 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
XIAP binds CASP7 (Mus musculus)
XIAP [cytosol] (Mus musculus)
XIAP:Caspase-7 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
Regulated Necrosis (Mus musculus)
RIPK1-mediated regulated necrosis (Mus musculus)
Regulation of necroptotic cell death (Mus musculus)
BIRC2/3 (cIAP1/2) is autoubiquitinated (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Death Receptor Signaling (Mus musculus)
TNF signaling (Mus musculus)
Regulation of TNFR1 signaling (Mus musculus)
CHUK, IKBKB phosphorylate RIPK1 at S25 (Mus musculus)
TNFα:TNFR1:TRADD:K63,Met1polyUb, p-S25-RIPK1:BIRC2/3:p-S-CHUK:p-S-IKBKB:IKBKG [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNFα:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2/3:p-S-CHUK:p-S-IKBKB:IKBKG [plasma membrane] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
CLIP3 and CYLD bind TNF signaling complex (Mus musculus)
CYLD:CLIP3:TNF:TNFR1:TRADD:K63pUb-RIP1:TRAF2:BIRC2/3 [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
CYLD:SPATA2:LUBAC binds TNFR1 signaling complex (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUb-RIPK1:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
K63polyUb-RIPK1 is deubiquitinated (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
LUBAC ubiquitinates RIPK1 at K627 (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
OPTN binds polyUb-RIPK1 within the TNFR1 complex (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
OPTN recruits CYLD to the TNFR1 complex (Mus musculus)
CYLD:OPTN:polyUb-RIPK1:TNFR1 complex [plasma membrane] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUb-RIPK1:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4:TAX1BP1:TNFAIP3 [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TBK1, IKBKE binds Met1-polyUb within the TNFR1 complex (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TBK1, IKBKE phosphorylate RIPK1 at T189 (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF-alpha:TNFR1:TRADD:p-T189,K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains (Mus musculus)
K48polyUb-RIPK1-containing TNFR1 complexes [plasma membrane] (Mus musculus)
RIPK1-containg TNFR1 signaling complexes [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
RIPK1-containg TNFR1 signaling complexes [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNFR1-induced NF-kappa-B signaling pathway (Mus musculus)
BIRC(cIAP1/2) ubiquitinates RIPK1 (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNFα:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2/3:CHUK:IKBKB:IKBKG [plasma membrane] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIP1:LUBAC:BIRC2/3:TAB1:TAK1:TAB2/3 [plasma membrane] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
TNFR1-induced proapoptotic signaling (Mus musculus)
TRADD:TRAF2:RIP1 complex dissociates from the TNF-α:TNF-R1 complex. (Mus musculus)
TNF-alpha:TNFR1:TRADD:p-T189,K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
Intracellular signaling by second messengers (Mus musculus)
PIP3 activates AKT signaling (Mus musculus)
PTEN Regulation (Mus musculus)
Regulation of PTEN localization (Mus musculus)
PTEN undergoes monoubiquitination (Mus musculus)
XIAP,NEDD4 [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
Regulation of PTEN stability and activity (Mus musculus)
NEDD4, WWP2, CHIP and XIAP polyubiquitinate PTEN (Mus musculus)
NEDD4,STUB1,WWP2 and XIAP [cytosol] (Mus musculus)
XIAP [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q60989
Reference Genes
BioGPS Gene:11798
ENSEMBL:ENSMUSG00000025860
ENSEMBL:ENSMUSG00000025860.16
KEGG Gene (Mus musculus):11798
Monarch:11798
NCBI Gene:11798
UCSC:Q60989
Reference Transcript
RefSeq:XM_017318360.1
RefSeq:NM_001301639.1
RefSeq:XM_011250977.2
RefSeq:XM_006541425.1
RefSeq:NM_001301641.1
RefSeq:XM_017318361.1
RefSeq:XM_017318362.1
RefSeq:XM_017318359.1
RefSeq:XM_006541427.1
RefSeq:NM_009688.3
Other Identifiers
10599369
116320_at
11798
137492_at
1421394_a_at
1426636_a_at
1437533_at
1450231_a_at
1456088_at
17534408
4525449
4556038
4799365
4837045
4850066
4856804
4898518
4918696
4950622
5080039
5114503
5197681
5226961
5231732
5240463
5506037
5570042
5611334
93400_at
93401_g_at
93402_i_at
A_51_P301216
A_51_P424893
A_55_P2052892
GE35076
GO:0002020
GO:0002376
GO:0003824
GO:0004842
GO:0005515
GO:0005634
GO:0005737
GO:0006915
GO:0006974
GO:0010804
GO:0012501
GO:0016055
GO:0016740
GO:0023052
GO:0031398
GO:0032481
GO:0032991
GO:0036211
GO:0042742
GO:0042802
GO:0042981
GO:0043027
GO:0043066
GO:0043067
GO:0043123
GO:0043226
GO:0043524
GO:0046330
GO:0046872
GO:0048471
GO:0051402
GO:0051726
GO:0060785
GO:0061135
GO:0061630
GO:0070427
GO:0070431
GO:0070534
GO:0090263
GO:0097110
GO:0098542
GO:0098772
GO:0120283
GO:0140096
GO:1902530
ILMN_1221270
ILMN_2739651
U36842_s_at
U88990_s_at
mMC022528
Participates
as a member of
NEDD4,STUB1,WWP2 and XIAP [cytosol] (Mus musculus)
as a candidate of
XIAP,NEDD4 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
as an input of
SEPT4 binds XIAP (Mus musculus)
SMAC (DIABLO) binds XIAP (Mus musculus)
XIAP binds CASP3 (Mus musculus)
XIAP binds CASP7 (Mus musculus)
XIAP binds CASP9 (Mus musculus)
as a component of
SEPT4 dimer:XIAP [cytosol] (Mus musculus)
XIAP:apoptosome [cytosol] (Mus musculus)
XIAP:Caspase-7 [cytosol] (Mus musculus)
DIABLO dimer:XIAP [cytosol] (Mus musculus)
XIAP:Caspase-3 [cytosol] (Mus musculus)
This entity regulates
Negatively
Cleavage of Procaspase-7 by the apoptosome
(Mus musculus)
Cleavage of Procaspase-3 by the apoptosome
(Mus musculus)
Other forms of this molecule
XIAP [nucleoplasm]
K48pUb-XIAP [cytosol]
Inferred From
XIAP [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_011249279.1
,
XP_017173850.1
,
XP_017173849.1
,
NP_001288570.1
,
NP_033818.2
,
XP_017173851.1
,
XP_006541490.1
,
XP_006541488.1
,
XP_017173848.1
,
NP_001288568.1
Ensembl
ENSMUST00000115095
,
ENSMUST00000115094
,
ENSMUSG00000025860
,
ENSMUSP00000061074
,
ENSMUSP00000110746
,
ENSMUSP00000110747
,
ENSMUSP00000026978
,
ENSMUST00000026978
,
ENSMUST00000055483
PRO
Q60989
MGI
107572
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P53702
1
Hccs [mitochondrial inner membrane]
(R-MMU-9866218)
0.591
5
UniProt:Q9NR28 DIABLO
2
DIABLO [mitochondrial intermembrane space]
(R-HSA-64637)
DIABLO [cytosol]
(R-HSA-114298)
0.564
3
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