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About
What is Reactome ?
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Team
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License Agreement
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Digital Preservation
Contact us
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Table of Contents
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Birc3 [cytosol]
Stable Identifier
R-MMU-50845
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
BIRC3, O08863
Locations in the PathwayBrowser
Expand all
Immune System (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
TNFR2 non-canonical NF-kB pathway (Mus musculus)
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway (Mus musculus)
TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds CD40 (Mus musculus)
CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF2:cIAP1,2 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF2:cIAP1,2 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TRAF2:TRAF1:cIAP1,2:TRAF3:NIK regulatory complex binds LTBR (Mus musculus)
3xLTBR:lymphotoxin,TNFSF14 trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF2:cIAP1,2 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF2:cIAP1,2 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TRAF2:cIAP1/2 complex binds FN14:TWEAK (Mus musculus)
3xFn14:TWEAK:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF2:cIAP1,2 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF2:cIAP1,2 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TRAF3 binds BAFFR:BAFF (Mus musculus)
3xBAFFR:BAFF trimer:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF2:cIAP1,2 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF2:cIAP1,2 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TRAFs bind RANK:RANKL (Mus musculus)
3xRANK:RANKL,sRANKL trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF2:cIAP1,2 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF2:cIAP1,2 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK (Mus musculus)
Non-canonical NF-kB initiating TNFRSF memebers [plasma membrane] (Mus musculus)
3xBAFFR:BAFF trimer:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF2:cIAP1,2 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
3xFn14:TWEAK:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF2:cIAP1,2 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
3xLTBR:lymphotoxin,TNFSF14 trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF2:cIAP1,2 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
3xRANK:RANKL,sRANKL trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF2:cIAP1,2 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
CD40:CD40L trimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF2:cIAP1,2 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNFA:TNFR2 heterotrimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF2:cIAP1,2 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TRAF3:NIK binds TRAF2:cIAP1/2 (Mus musculus)
TRAF2:cIAP1,2 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF2:cIAP1,2 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
cIAP1,2 ubiquitinates NIK in cIAP1,2:TRAF2::TRAF3:NIK (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TRAF2:cIAP1,2 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF2:cIAP1,2 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK complex binds TNFR2 trimer (Mus musculus)
TNFA:TNFR2 heterotrimer:cIAP1,2:TRAF2:TRAF3:NIK [plasma membrane] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF2:cIAP1,2 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
cIAP1,2:TRAF2:TRAF3:NIK [cytosol] (Mus musculus)
TRAF2:cIAP1,2 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
Innate Immune System (Mus musculus)
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Mus musculus)
NOD1/2 Signaling Pathway (Mus musculus)
RIP2 is K63 polyubiquitinated (Mus musculus)
RIP2 ubiquitin ligases [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
Toll-like Receptor Cascades (Mus musculus)
Toll Like Receptor 4 (TLR4) Cascade (Mus musculus)
MyD88-independent TLR4 cascade (Mus musculus)
TRIF (TICAM1)-mediated TLR4 signaling (Mus musculus)
IKK complex recruitment mediated by RIP1 (Mus musculus)
K63-linked ubiquitination of RIP1 bound to the activated TLR complex (Mus musculus)
RIP1 ubiqutin ligases [cytosol] (Mus musculus)
c-IAP2:UBE2D [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Deubiquitination (Mus musculus)
Ub-specific processing proteases (Mus musculus)
USP19 binds HIF1A,BIRC2,BIRC3 (Mus musculus)
HIF1A,BIRC2,BIRC3 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
USP19:HIF1A,BIRC2,BIRC3 [cytosol] (Mus musculus)
HIF1A,BIRC2,BIRC3 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
Programmed Cell Death (Mus musculus)
Regulated Necrosis (Mus musculus)
RIPK1-mediated regulated necrosis (Mus musculus)
Regulation of necroptotic cell death (Mus musculus)
BIRC2/3 (cIAP1/2) is autoubiquitinated (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Death Receptor Signaling (Mus musculus)
TNF signaling (Mus musculus)
Regulation of TNFR1 signaling (Mus musculus)
CHUK, IKBKB phosphorylate RIPK1 at S25 (Mus musculus)
TNFα:TNFR1:TRADD:K63,Met1polyUb, p-S25-RIPK1:BIRC2/3:p-S-CHUK:p-S-IKBKB:IKBKG [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNFα:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2/3:p-S-CHUK:p-S-IKBKB:IKBKG [plasma membrane] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
CLIP3 and CYLD bind TNF signaling complex (Mus musculus)
CYLD:CLIP3:TNF:TNFR1:TRADD:K63pUb-RIP1:TRAF2:BIRC2/3 [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
CYLD hydrolyses K63polyUb on RIPK1 within the TNFR1 complex (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
CYLD hydrolyses M1polyUb on RIPK1 within the TNFR1 complex (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
CYLD:SPATA2:LUBAC binds TNFR1 signaling complex (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUb-RIPK1:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
K63polyUb-RIPK1 is deubiquitinated (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
LUBAC ubiquitinates RIPK1 at K627 (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
OPTN binds polyUb-RIPK1 within the TNFR1 complex (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
OPTN recruits CYLD to the TNFR1 complex (Mus musculus)
CYLD:OPTN:polyUb-RIPK1:TNFR1 complex [plasma membrane] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
SPATA2:CYLD-bound LUBAC ubiquitinates RIPK1 at K627 within the TNFR1 signaling complex (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUb-RIPK1:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TAX1BP1:TNFAIP3(A20) binds RIPK1-containing complexes (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4:TAX1BP1:TNFAIP3 [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TBK1, IKBKE binds Met1-polyUb within the TNFR1 complex (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TBK1, IKBKE phosphorylate RIPK1 at T189 (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF-alpha:TNFR1:TRADD:p-T189,K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNFAIP3 (A20) ubiquitinates RIPK1 with K48-linked Ub chains (Mus musculus)
K48polyUb-RIPK1-containing TNFR1 complexes [plasma membrane] (Mus musculus)
RIPK1-containg TNFR1 signaling complexes [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
RIPK1-containg TNFR1 signaling complexes [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNFR1-induced NF-kappa-B signaling pathway (Mus musculus)
BIRC(cIAP1/2) ubiquitinates RIPK1 (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2,3:LUBAC recruits IKKA:IKBKB:IKBKG (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUB-RIPK1:LUBAC:OPTN [plasma membrane] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:polyUb-RIPK1:LUBAC [plasma membrane] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNFα:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2/3:CHUK:IKBKB:IKBKG [plasma membrane] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIPK1:BIRC2/3:LUBAC recruits TAK1 complex (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:K63polyUb-RIP1:LUBAC:BIRC2/3:TAB1:TAK1:TAB2/3 [plasma membrane] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:BIRC2/3:K63polyUB-RIP1:LUBAC [plasma membrane] (Mus musculus)
TNF-α:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2,3,4 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF:TNFR1:TRADD:TRAF2:RIPK1 recruits BIRC2/3 (cIAP1/2) (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNF-α:TNFR1:TRADD:RIP1:TRAF2:BIRC2/3 [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
TNFR1-induced proapoptotic signaling (Mus musculus)
TRADD:TRAF2:RIP1 dissociates from TNF-α:TNFR1 (Mus musculus)
TNF-alpha:TNFR1:TRADD:p-T189,K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
Birc3 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:O08863
Gene Names
Birc3
Reference Genes
BioGPS Gene:11796 Birc3
ENSEMBL:ENSMUSG00000032000
KEGG:mmu:11796 Birc3
Monarch:11796 Birc3
NCBI Gene:11796 Birc3
UCSC:O08863 Birc3
Reference Transcript
RefSeq:NM_007464.3 Birc3
Participates
as a member of
HIF1A,BIRC2,BIRC3 [cytosol] (Mus musculus)
BIRC2,3,4 [cytosol] (Mus musculus)
as a component of
c-IAP2:UBE2D [cytosol] (Mus musculus)
as a candidate of
RIP2 ubiquitin ligases [cytosol] (Mus musculus)
Other forms of this molecule
Birc3 [cytosol]
Birc3 [cytosol]
Inferred From
BIRC3 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_031490.2
PRO
O08863
MGI
1197007
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