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APAF1 [cytosol]
Stable Identifier
R-MMU-50099
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
O88879
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Mus musculus)
Apoptosis (Mus musculus)
Intrinsic Pathway for Apoptosis (Mus musculus)
Apoptotic factor-mediated response (Mus musculus)
Cytochrome c-mediated apoptotic response (Mus musculus)
Activation of caspases through apoptosome-mediated cleavage (Mus musculus)
Cleavage of Procaspase-3 by the apoptosome (Mus musculus)
Apoptosome [cytosol] (Mus musculus)
APAF1:CYCS [cytosol] (Mus musculus)
APAF1 [cytosol] (Mus musculus)
Cleavage of Procaspase-7 by the apoptosome (Mus musculus)
Apoptosome [cytosol] (Mus musculus)
APAF1:CYCS [cytosol] (Mus musculus)
APAF1 [cytosol] (Mus musculus)
Formation of apoptosome (Mus musculus)
CYCS binds to APAF1 (Mus musculus)
APAF1:ADP [cytosol] (Mus musculus)
APAF1 [cytosol] (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
APAF1:ATP [cytosol] (Mus musculus)
APAF1 [cytosol] (Mus musculus)
CYCS:APAF1 binds procaspase-9 (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
APAF1:ATP [cytosol] (Mus musculus)
APAF1 [cytosol] (Mus musculus)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
APAF1:ATP [cytosol] (Mus musculus)
APAF1 [cytosol] (Mus musculus)
Cleavage of Procaspase‑9 to caspase‑9 (Mus musculus)
APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol] (Mus musculus)
APAF1:CYCS [cytosol] (Mus musculus)
APAF1 [cytosol] (Mus musculus)
Apoptosome [cytosol] (Mus musculus)
APAF1:CYCS [cytosol] (Mus musculus)
APAF1 [cytosol] (Mus musculus)
Procaspase 9 forms dimer (Mus musculus)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
APAF1:ATP [cytosol] (Mus musculus)
APAF1 [cytosol] (Mus musculus)
APAF1:CYCS:ATP:CASP9(1-416)dimer [cytosol] (Mus musculus)
APAF1:CYCS [cytosol] (Mus musculus)
APAF1 [cytosol] (Mus musculus)
Regulation of the apoptosome activity (Mus musculus)
APAF1 binds AVEN (Mus musculus)
APAF1:ADP [cytosol] (Mus musculus)
APAF1 [cytosol] (Mus musculus)
APAF1:AVEN [cytosol] (Mus musculus)
APAF1:ADP [cytosol] (Mus musculus)
APAF1 [cytosol] (Mus musculus)
APAF1:CYCS binds APIP (Mus musculus)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
APAF1:ATP [cytosol] (Mus musculus)
APAF1 [cytosol] (Mus musculus)
APAF1:CYCS:ATP:APIP [cytosol] (Mus musculus)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
APAF1:ATP [cytosol] (Mus musculus)
APAF1 [cytosol] (Mus musculus)
CASP9 is phosphorylated at T412 (Mus musculus)
APAF1:ATP:CYCS heptamer:CASP9 [cytosol] (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
APAF1:ATP [cytosol] (Mus musculus)
APAF1 [cytosol] (Mus musculus)
APAF1:ATP:CYCS heptamer:p-T412-CASP9 [cytosol] (Mus musculus)
APAF1:ATP:CYCS [cytosol] (Mus musculus)
APAF1:ATP [cytosol] (Mus musculus)
APAF1 [cytosol] (Mus musculus)
XIAP binds CASP9 (Mus musculus)
Apoptosome [cytosol] (Mus musculus)
APAF1:CYCS [cytosol] (Mus musculus)
APAF1 [cytosol] (Mus musculus)
XIAP:apoptosome [cytosol] (Mus musculus)
Apoptosome [cytosol] (Mus musculus)
APAF1:CYCS [cytosol] (Mus musculus)
APAF1 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:O88879 Apaf1
Gene Names
Apaf1
Chain
chain:1-1249
Reference Genes
BioGPS Gene:11783 Apaf1
ENSEMBL:ENSMUSG00000019979.13 Apaf1
KEGG Gene (Mus musculus):11783 Apaf1
Monarch:11783 Apaf1
NCBI Gene:11783 Apaf1
UCSC:O88879 Apaf1
Reference Transcript
RefSeq:NM_009684.2 Apaf1
RefSeq:NM_001042558.1 Apaf1
Other Identifiers
10371846
103796_at
11783
1450223_at
1452870_at
17244140
4331728
4392108
4411564
4416189
4463688
4475278
4503091
4536942
4558868
4587395
4612872
4692287
4807027
4807916
4812275
4853808
4868983
4877085
4935685
4958883
4961965
4965106
4994368
5014009
5140167
5146351
5267962
5283655
5287567
5302421
5313540
5317049
5353573
5355033
5371342
5431056
5437030
5471480
5526940
5554695
5602357
A_51_P368696
A_51_P417701
A_52_P621991
GO:0000166
GO:0001666
GO:0001822
GO:0001843
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0006915
GO:0007420
GO:0007584
GO:0008656
GO:0010659
GO:0012501
GO:0023052
GO:0030154
GO:0030900
GO:0031072
GO:0032991
GO:0042802
GO:0042981
GO:0043226
GO:0043293
GO:0043531
GO:0048856
GO:0051402
GO:0070059
GO:0071560
GO:0097190
GO:0097193
GO:0098772
GO:1902510
GO:2001235
ILMN_1228561
ILMN_2466335
ILMN_3143577
mMC022280
mMC023311
Participates
as a component of
APAF1:ADP [cytosol] (Mus musculus)
APAF1:ATP [cytosol] (Mus musculus)
APAF1:CYCS [cytosol] (Mus musculus)
Other forms of this molecule
APAF1 [secretory granule lumen]
APAF1 [extracellular region]
APAF1 [ficolin-1-rich granule lumen]
Apaf1 [cytosol]
Inferred From
APAF1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_033814.2
,
NP_001036023.1
Ensembl
ENSMUST00000159110
,
ENSMUSP00000125291
,
ENSMUST00000020157
,
ENSMUSP00000020157
,
ENSMUSG00000019979
PRO
O88879
MGI
1306796
PDB
3SFZ
,
3SHF
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