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IL2:IL2RA:IL2RB:JAK1 [plasma membrane]
Stable Identifier
R-MMU-450065
Type
Complex
Species
Mus musculus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
Signaling by Interleukins (Mus musculus)
Interleukin-2 family signaling (Mus musculus)
Interleukin-2 signaling (Mus musculus)
Interleukin-2 receptor alpha:IL2 binds Interleukin-2 receptor beta (Mus musculus)
IL2:IL2RA:IL2RB:JAK1 [plasma membrane] (Mus musculus)
Interleukin-2: IL2 receptor alpha:beta binds IL2 receptor gamma subunit (Mus musculus)
IL2:IL2R trimer:JAK1:JAK3 [plasma membrane] (Mus musculus)
IL2:IL2RA:IL2RB:JAK1 [plasma membrane] (Mus musculus)
IL2:IL2RA:IL2RB:JAK1 [plasma membrane] (Mus musculus)
Within the IL-2R complex JAK3 phosphorylates JAK1 (Mus musculus)
IL2:IL2R trimer:JAK1:JAK3 [plasma membrane] (Mus musculus)
IL2:IL2RA:IL2RB:JAK1 [plasma membrane] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
IL2:IL2RA [plasma membrane]
(Mus musculus)
IL2RB:JAK1 [plasma membrane]
(Mus musculus)
Participates
as an input of
Interleukin-2: IL2 receptor alpha:beta binds IL2 receptor gamma subunit (Mus musculus)
as an output of
Interleukin-2 receptor alpha:IL2 binds Interleukin-2 receptor beta (Mus musculus)
as a component of
IL2:IL2R trimer:JAK1:JAK3 [plasma membrane] (Mus musculus)
Inferred From
IL2:IL2RA:IL2RB:JAK1 [plasma membrane]
(Homo sapiens)
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