Reactome | Rln3 [extracellular region]

Rln3 [extracellular region]

Stable Identifier

R-MMU-444849

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

extracellular region

Synonyms

RLN3(26-52), Q8CHK2

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (i) signalling events (Mus musculus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        RXFP3:Relaxin-3 [plasma membrane] (Mus musculus)
        
        Relaxin-3 [extracellular region] (Mus musculus)
        
        Rln3 [extracellular region] (Mus musculus)
        
        RXFP4:RXFP4 ligands [plasma membrane] (Mus musculus)
        
        RXFP4 ligands [extracellular region] (Mus musculus)
        
        Relaxin-3 [extracellular region] (Mus musculus)
        
        Rln3 [extracellular region] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        RXFP3:Relaxin-3 [plasma membrane] (Mus musculus)
        
        Relaxin-3 [extracellular region] (Mus musculus)
        
        Rln3 [extracellular region] (Mus musculus)
        
        RXFP4:RXFP4 ligands [plasma membrane] (Mus musculus)
        
        RXFP4 ligands [extracellular region] (Mus musculus)
        
        Relaxin-3 [extracellular region] (Mus musculus)
        
        Rln3 [extracellular region] (Mus musculus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        RXFP3:Relaxin-3 [plasma membrane] (Mus musculus)
        
        Relaxin-3 [extracellular region] (Mus musculus)
        
        Rln3 [extracellular region] (Mus musculus)
        
        RXFP4:RXFP4 ligands [plasma membrane] (Mus musculus)
        
        RXFP4 ligands [extracellular region] (Mus musculus)
        
        Relaxin-3 [extracellular region] (Mus musculus)
        
        Rln3 [extracellular region] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        RXFP3:Relaxin-3 [plasma membrane] (Mus musculus)
        
        Relaxin-3 [extracellular region] (Mus musculus)
        
        Rln3 [extracellular region] (Mus musculus)
        
        RXFP4:RXFP4 ligands [plasma membrane] (Mus musculus)
        
        RXFP4 ligands [extracellular region] (Mus musculus)
        
        Relaxin-3 [extracellular region] (Mus musculus)
        
        Rln3 [extracellular region] (Mus musculus)
      - The Ligand:GPCR:Gi complex dissociates (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        RXFP3:Relaxin-3 [plasma membrane] (Mus musculus)
        
        Relaxin-3 [extracellular region] (Mus musculus)
        
        Rln3 [extracellular region] (Mus musculus)
        
        RXFP4:RXFP4 ligands [plasma membrane] (Mus musculus)
        
        RXFP4 ligands [extracellular region] (Mus musculus)
        
        Relaxin-3 [extracellular region] (Mus musculus)
        
        Rln3 [extracellular region] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        RXFP3:Relaxin-3 [plasma membrane] (Mus musculus)
        
        Relaxin-3 [extracellular region] (Mus musculus)
        
        Rln3 [extracellular region] (Mus musculus)
        
        RXFP4:RXFP4 ligands [plasma membrane] (Mus musculus)
        
        RXFP4 ligands [extracellular region] (Mus musculus)
        
        Relaxin-3 [extracellular region] (Mus musculus)
        
        Rln3 [extracellular region] (Mus musculus)
    - G alpha (s) signalling events (Mus musculus)
      - Liganded Gs-activating GPCR acts as a GEF for Gs (Mus musculus)
        
        GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Mus musculus)
        
        RXFP1:Relaxin-2,Relaxin-3 [plasma membrane] (Mus musculus)
        
        Relaxin-2, Relaxin-3 [extracellular region] (Mus musculus)
        
        Relaxin-3 [extracellular region] (Mus musculus)
        
        Rln3 [extracellular region] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Mus musculus)
        
        RXFP1:Relaxin-2,Relaxin-3 [plasma membrane] (Mus musculus)
        
        Relaxin-2, Relaxin-3 [extracellular region] (Mus musculus)
        
        Relaxin-3 [extracellular region] (Mus musculus)
        
        Rln3 [extracellular region] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Peptide ligand-binding receptors (Mus musculus)
        
        Relaxin receptors (Mus musculus)
        
        Relaxin 3 receptor 1 binds relaxin 3 (Mus musculus)
        
        RXFP3:Relaxin-3 [plasma membrane] (Mus musculus)
        
        Relaxin-3 [extracellular region] (Mus musculus)
        
        Rln3 [extracellular region] (Mus musculus)
        
        Relaxin-3 [extracellular region] (Mus musculus)
        
        Rln3 [extracellular region] (Mus musculus)
        
        Relaxin 3 receptor 2 binds relaxin 3 and INSL5 (Mus musculus)
        
        RXFP4 ligands [extracellular region] (Mus musculus)
        
        Relaxin-3 [extracellular region] (Mus musculus)
        
        Rln3 [extracellular region] (Mus musculus)
        
        RXFP4:RXFP4 ligands [plasma membrane] (Mus musculus)
        
        RXFP4 ligands [extracellular region] (Mus musculus)
        
        Relaxin-3 [extracellular region] (Mus musculus)
        
        Rln3 [extracellular region] (Mus musculus)
        
        Relaxin receptor 1 binds relaxin 2 and 3 (Mus musculus)
        
        RXFP1:Relaxin-2,Relaxin-3 [plasma membrane] (Mus musculus)
        
        Relaxin-2, Relaxin-3 [extracellular region] (Mus musculus)
        
        Relaxin-3 [extracellular region] (Mus musculus)
        
        Rln3 [extracellular region] (Mus musculus)
        
        Relaxin-2, Relaxin-3 [extracellular region] (Mus musculus)
        
        Relaxin-3 [extracellular region] (Mus musculus)
        
        Rln3 [extracellular region] (Mus musculus)

External Reference Information

External Reference

UniProt:Q8CHK2

Gene Names

Rln3

Reference Genes

BioGPS Gene:212108 Rln3

ENSEMBL:ENSMUSG00000045232

ENSEMBL:ENSMUSG00000045232.5 Rln3

KEGG Gene (Mus musculus):212108 Rln3

Monarch:212108 Rln3

NCBI Gene:212108 Rln3

UCSC:Q8CHK2 Rln3

Reference Transcript

RefSeq:NM_173184.1 Rln3

Other Identifiers

10580077

17511011

212108

4580268

4698598

4893592

5432770

A_51_P201581

A_66_P112749

GE1520808

GO:0001664

GO:0005179

GO:0005576

GO:0007165

GO:0023052

GO:0048018

GO:0098772

ILMN_2619211

mMC004637

Participates

as a component of

Relaxin-3 [extracellular region] (Mus musculus)

Other forms of this molecule

Rln3 [extracellular region]

Inferred From

RLN3(26-52) [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_775276.1

Ensembl

ENSMUSG00000045232, ENSMUSP00000051392, ENSMUST00000061923

PRO

Q8CHK2

MGI

2158015

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