Reactome | Tas1r1 [plasma membrane]

Tas1r1 [plasma membrane]

Stable Identifier

R-MMU-444666

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

TAS1R1, Q99PG6

Locations in the PathwayBrowser

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Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (i) signalling events (Mus musculus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS1R1:TAS1R3:L-Glu [plasma membrane] (Mus musculus)
        
        TAS1R1:TAS1R3 [plasma membrane] (Mus musculus)
        
        Tas1r1 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS1R1:TAS1R3:L-Glu [plasma membrane] (Mus musculus)
        
        TAS1R1:TAS1R3 [plasma membrane] (Mus musculus)
        
        Tas1r1 [plasma membrane] (Mus musculus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS1R1:TAS1R3:L-Glu [plasma membrane] (Mus musculus)
        
        TAS1R1:TAS1R3 [plasma membrane] (Mus musculus)
        
        Tas1r1 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS1R1:TAS1R3:L-Glu [plasma membrane] (Mus musculus)
        
        TAS1R1:TAS1R3 [plasma membrane] (Mus musculus)
        
        Tas1r1 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gi complex dissociates (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS1R1:TAS1R3:L-Glu [plasma membrane] (Mus musculus)
        
        TAS1R1:TAS1R3 [plasma membrane] (Mus musculus)
        
        Tas1r1 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS1R1:TAS1R3:L-Glu [plasma membrane] (Mus musculus)
        
        TAS1R1:TAS1R3 [plasma membrane] (Mus musculus)
        
        Tas1r1 [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Mus musculus)
      - T1R1/T1R3 dimer is the umami taste receptor (Mus musculus)
        
        TAS1R1:TAS1R3 [plasma membrane] (Mus musculus)
        
        Tas1r1 [plasma membrane] (Mus musculus)
        
        TAS1R1:TAS1R3:L-Glu [plasma membrane] (Mus musculus)
        
        TAS1R1:TAS1R3 [plasma membrane] (Mus musculus)
        
        Tas1r1 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q99PG6

Gene Names

Tas1r1

Reference Genes

BioGPS Gene:110326 Tas1r1

ENSEMBL:ENSMUSG00000028950

KEGG Gene (Mus musculus):110326 Tas1r1

Monarch:110326 Tas1r1

NCBI Gene:110326 Tas1r1

Reference Transcript

RefSeq:NM_031867.2 Tas1r1

Participant Of

hasComponent

TAS1R1:TAS1R3 [plasma membrane]

Inferred From

TAS1R1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_114073.1

PRO

Q99PG6

MGI

1927505