Reactome | Gpr65 [plasma membrane]

Gpr65 [plasma membrane]

Stable Identifier

R-MMU-444624

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

GPR65, Q61038

Locations in the PathwayBrowser

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Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (q) signalling events (Mus musculus)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        pH sensing receptors:H+ [plasma membrane] (Mus musculus)
        
        pH sensing receptors [plasma membrane] (Mus musculus)
        
        Gpr65 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        pH sensing receptors:H+ [plasma membrane] (Mus musculus)
        
        pH sensing receptors [plasma membrane] (Mus musculus)
        
        Gpr65 [plasma membrane] (Mus musculus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        pH sensing receptors:H+ [plasma membrane] (Mus musculus)
        
        pH sensing receptors [plasma membrane] (Mus musculus)
        
        Gpr65 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        pH sensing receptors:H+ [plasma membrane] (Mus musculus)
        
        pH sensing receptors [plasma membrane] (Mus musculus)
        
        Gpr65 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gq complex dissociates (Mus musculus)
        
        GPCRs that activate Gq/11 [plasma membrane] (Mus musculus)
        
        pH sensing receptors [plasma membrane] (Mus musculus)
        
        Gpr65 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        pH sensing receptors:H+ [plasma membrane] (Mus musculus)
        
        pH sensing receptors [plasma membrane] (Mus musculus)
        
        Gpr65 [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - GPR4, GPR65, GPR132 and OGR1 are pH sensing receptors (Mus musculus)
        
        pH sensing receptors [plasma membrane] (Mus musculus)
        
        Gpr65 [plasma membrane] (Mus musculus)
        
        pH sensing receptors:H+ [plasma membrane] (Mus musculus)
        
        pH sensing receptors [plasma membrane] (Mus musculus)
        
        Gpr65 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q61038

Gene Names

Gpr65

Reference Genes

BioGPS Gene:14744 Gpr65

ENSEMBL:ENSMUSG00000021886

KEGG Gene (Mus musculus):14744 Gpr65

Monarch:14744 Gpr65

NCBI Gene:14744 Gpr65

Reference Transcript

RefSeq:NM_008152.3 Gpr65

Participant Of

hasMember

pH sensing receptors [plasma membrane]

Inferred From

GPR65 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_032178.1

PRO

Q61038

MGI

108031