Reactome | Tas1r2 [plasma membrane]

Tas1r2 [plasma membrane]

Stable Identifier

R-MMU-444622

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

TAS1R2, Q925I4

Locations in the PathwayBrowser

Expand all

Sensory Perception (Mus musculus)

- Sensory perception of taste (Mus musculus)
  - Sensory perception of sweet, bitter, and umami (glutamate) taste (Mus musculus)
    - Sweet compound binds sweet taste receptor (TAS1R2:TAS1R3) (Mus musculus)
      - TAS1R2:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Mus musculus)
        
        TAS1R2:TAS1R3 [plasma membrane] (Mus musculus)
        
        Tas1r2 [plasma membrane] (Mus musculus)
      - TAS1R2:TAS1R3:Sweet compound:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Mus musculus)
        
        TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
        
        TAS1R2:TAS1R3 [plasma membrane] (Mus musculus)
        
        Tas1r2 [plasma membrane] (Mus musculus)

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (i) signalling events (Mus musculus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
        
        TAS1R2:TAS1R3 [plasma membrane] (Mus musculus)
        
        Tas1r2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
        
        TAS1R2:TAS1R3 [plasma membrane] (Mus musculus)
        
        Tas1r2 [plasma membrane] (Mus musculus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
        
        TAS1R2:TAS1R3 [plasma membrane] (Mus musculus)
        
        Tas1r2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
        
        TAS1R2:TAS1R3 [plasma membrane] (Mus musculus)
        
        Tas1r2 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gi complex dissociates (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
        
        TAS1R2:TAS1R3 [plasma membrane] (Mus musculus)
        
        Tas1r2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
        
        TAS1R2:TAS1R3 [plasma membrane] (Mus musculus)
        
        Tas1r2 [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Mus musculus)
      - T1R2/T1R3 dimer is a sweet taste receptor (Mus musculus)
        
        TAS1R2:TAS1R3 [plasma membrane] (Mus musculus)
        
        Tas1r2 [plasma membrane] (Mus musculus)
        
        TAS1R2:TAS1R3:Sweet taste compounds [plasma membrane] (Mus musculus)
        
        TAS1R2:TAS1R3 [plasma membrane] (Mus musculus)
        
        Tas1r2 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q925I4

Gene Names

Tas1r2

Reference Genes

BioGPS Gene:83770 Tas1r2

ENSEMBL:ENSMUSG00000028738

ENSEMBL:ENSMUSG00000028738.15 Tas1r2

KEGG Gene (Mus musculus):83770 Tas1r2

Monarch:83770 Tas1r2

NCBI Gene:83770 Tas1r2

UCSC:Q925I4 Tas1r2

Reference Transcript

RefSeq:NM_031873.1 Tas1r2

Other Identifiers

10509811

1450313_at

17420800

4666153

4739446

5153777

5154609

5251434

5363324

5455303

5592744

83770

A_51_P277756

A_55_P2744042

GE41689

GO:0000910

GO:0001582

GO:0004930

GO:0005515

GO:0005886

GO:0007165

GO:0007186

GO:0008527

GO:0016020

GO:0023052

GO:0032467

GO:0033041

GO:0043235

GO:0050877

GO:0050896

GO:0050909

GO:0050916

GO:0060089

GO:1903767

ILMN_2714817

mMC002729

Participates

as a component of

TAS1R2:TAS1R3 [plasma membrane] (Mus musculus)

Inferred From

TAS1R2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_114079.1

Ensembl

ENSMUST00000030510, ENSMUSP00000030510, ENSMUSG00000028738

PRO

Q925I4

MGI

1933546

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