Ccnd1:Crebbp binds Notch1 promoter

Stable Identifier
R-MMU-4395232
Type
Reaction [binding]
Species
Mus musculus
Compartment
ReviewStatus
5/5
General
SVG |   | PPTX  | SBGN
Ccnd1:Crebbp binds Notch1 promoter
In mouse retina, Ccnd1 (cyclin D1) forms a complex with Crebbp and binds Notch1 promoter, stimulating Notch1 transcription. Positive effect of Ccnd1 on Notch1 transcription is also observed in R28 rat retinal precursor cells (Bienvenu et al. 2010).
Literature References
PubMed ID Title Journal Year
20090754 Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen

Gygi, SP, Liu, XS, Geng, Y, Mizeracka, K, Jirawatnotai, S, Meyer, CA, Elias, JE, Cole, MF, Sicinski, P, Bienvenu, F, Young, RA, Frampton, GM, Odajima, J, Cepko, CL, Zagozdzon, A, Jecrois, M, Odom, DT, Marson, A

Nature 2010
Participants
Orthologous Events
Authored
Reviewed
Created
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