Znt3 transports zinc into synaptic vesicles

Stable Identifier
R-MMU-437092
Type
Reaction [transition]
Species
Mus musculus
Compartment
synaptic vesicle membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Znt3 transports zinc into synaptic vesicles

Rat Znt3 is localized to the brain and testis. Immunohistochemical staining indicates Znt3 is localized to synaptic vesicle membranes and that it participates in the transport of zinc in these vesicles (Palmiter RD et al, 1996; Wenzel HJ et al, 1997)

Literature References
PubMed ID Title Journal Year
9356509 Ultrastructural localization of zinc transporter-3 (ZnT-3) to synaptic vesicle membranes within mossy fiber boutons in the hippocampus of mouse and monkey

Schwartzkroin, PA, Cole, TB, Palmiter, RD, Born, DE, Wenzel, HJ

Proc Natl Acad Sci U S A 1997
8962159 ZnT-3, a putative transporter of zinc into synaptic vesicles

Findley, SD, Cole, TB, Quaife, CJ, Palmiter, RD

Proc Natl Acad Sci U S A 1996
Participants
Input
Output
Catalyst Activity

zinc ion transmembrane transporter activity of Znt3 [synaptic vesicle membrane]

Physical Entity
Znt3 [synaptic vesicle membrane] (Mus musculus)
Activity
zinc ion transmembrane transporter activity (GO:0005385)
Orthologous Events
ZnT3 transports zinc into synaptic vesicles (Homo sapiens)
Authored
Jassal, B  (2009-09-11)
Reviewed
He, L  (2009-11-12)
Created
Jassal, B  (2009-09-11)
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