Reactome | GRM6 [plasma membrane]

GRM6 [plasma membrane]

Stable Identifier

R-MMU-420574

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

Q5NCH9

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (i) signalling events (Mus musculus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Mus musculus)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Mus musculus)
        
        GRM6 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Mus musculus)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Mus musculus)
        
        GRM6 [plasma membrane] (Mus musculus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Mus musculus)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Mus musculus)
        
        GRM6 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Mus musculus)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Mus musculus)
        
        GRM6 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gi complex dissociates (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Mus musculus)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Mus musculus)
        
        GRM6 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Mus musculus)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Mus musculus)
        
        GRM6 [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Mus musculus)
      - Metabotropic glutamate receptors bind glutamate (Mus musculus)
        
        GRM1-8 [plasma membrane] (Mus musculus)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Mus musculus)
        
        GRM6 [plasma membrane] (Mus musculus)
        
        GRM1-8:L-Glu [plasma membrane] (Mus musculus)
        
        GRM1-8 [plasma membrane] (Mus musculus)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Mus musculus)
        
        GRM6 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q5NCH9

Reference Genes

BioGPS Gene:108072

ENSEMBL:ENSMUSG00000000617

ENSEMBL:ENSMUSG00000000617.15

KEGG Gene (Mus musculus):108072

Monarch:108072

NCBI Gene:108072

UCSC:Q5NCH9

Reference Transcript

Other Identifiers

10375774

108072

17249234

4435703

4497192

4588243

4616332

4699564

4737035

4842570

4873178

4881913

4991661

5067897

5074534

5155680

5449079

5550946

A_51_P224938

A_55_P1990623

GE138535

GO:0000139

GO:0001640

GO:0001642

GO:0004930

GO:0005783

GO:0005789

GO:0005794

GO:0005886

GO:0007154

GO:0007165

GO:0007186

GO:0007196

GO:0007216

GO:0007268

GO:0007601

GO:0007626

GO:0008066

GO:0016020

GO:0023052

GO:0030425

GO:0035841

GO:0042803

GO:0042995

GO:0043226

GO:0045211

GO:0048856

GO:0050877

GO:0050896

GO:0050908

GO:0050953

GO:0051966

GO:0055085

GO:0060041

GO:0060089

GO:1905665

ILMN_3162124

ILMN_3162125

Msa.26869.0_s_at

mMC014908

Participates

as a member of

GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Mus musculus)

Inferred From

GRM6 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_775548.2, XP_006532024.1

Ensembl

ENSMUST00000171427, ENSMUST00000000631, ENSMUSP00000130728, ENSMUSP00000000631, ENSMUSG00000000617

PRO

Q5NCH9

MGI

1351343

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