Reactome | S1pr2 [plasma membrane]

S1pr2 [plasma membrane]

Stable Identifier

R-MMU-419419

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

S1PR2, P52592

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (i) signalling events (Mus musculus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        S1PR2-5:S1P [plasma membrane] (Mus musculus)
        
        S1PR2-5 [plasma membrane] (Mus musculus)
        
        S1pr2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        S1PR2-5:S1P [plasma membrane] (Mus musculus)
        
        S1PR2-5 [plasma membrane] (Mus musculus)
        
        S1pr2 [plasma membrane] (Mus musculus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        S1PR2-5:S1P [plasma membrane] (Mus musculus)
        
        S1PR2-5 [plasma membrane] (Mus musculus)
        
        S1pr2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        S1PR2-5:S1P [plasma membrane] (Mus musculus)
        
        S1PR2-5 [plasma membrane] (Mus musculus)
        
        S1pr2 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gi complex dissociates (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        S1PR2-5:S1P [plasma membrane] (Mus musculus)
        
        S1PR2-5 [plasma membrane] (Mus musculus)
        
        S1pr2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        S1PR2-5:S1P [plasma membrane] (Mus musculus)
        
        S1PR2-5 [plasma membrane] (Mus musculus)
        
        S1pr2 [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Lysosphingolipid and LPA receptors (Mus musculus)
        
        S1PR2-5 bind S1P (Mus musculus)
        
        S1PR2-5 [plasma membrane] (Mus musculus)
        
        S1pr2 [plasma membrane] (Mus musculus)
        
        S1PR2-5:S1P [plasma membrane] (Mus musculus)
        
        S1PR2-5 [plasma membrane] (Mus musculus)
        
        S1pr2 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P52592

Gene Names

S1pr2

Reference Genes

BioGPS Gene:14739 S1pr2

ENSEMBL:ENSMUSG00000043895

ENSEMBL:ENSMUSG00000043895.7 S1pr2

KEGG Gene (Mus musculus):14739 S1pr2

Monarch:14739 S1pr2

NCBI Gene:14739 S1pr2

UCSC:P52592 S1pr2

Reference Transcript

Other Identifiers

10591412

114005_at

1428176_at

1447224_at

14739

17524578

4393995

4865275

4875925

4921118

4959763

5036461

5049056

5335646

5354593

5524254

99372_at

A_51_P499871

A_52_P604613

GE1567053

GE38392

GO:0001664

GO:0003376

GO:0004930

GO:0005178

GO:0005515

GO:0005737

GO:0005886

GO:0007010

GO:0007165

GO:0007186

GO:0007189

GO:0008528

GO:0010800

GO:0014912

GO:0016020

GO:0019222

GO:0023052

GO:0030036

GO:0030154

GO:0036211

GO:0038036

GO:0046847

GO:0048856

GO:0048870

GO:0050877

GO:0060079

GO:0060089

GO:0090394

GO:0098794

GO:1903142

GO:1904706

ILMN_2773936

ILMN_2964522

mMC018288

Participates

as a member of

S1PR2-5 [plasma membrane] (Mus musculus)

Inferred From

S1PR2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_006510082.1, NP_034463.2

Ensembl

ENSMUSG00000043895, ENSMUSP00000053394, ENSMUST00000054197

PRO

P52592

MGI

99569