Reactome | Lpar2 [plasma membrane]

Lpar2 [plasma membrane]

Stable Identifier

R-MMU-419393

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

LPAR2, Q9JL06

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (i) signalling events (Mus musculus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar2 [plasma membrane] (Mus musculus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar2 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gi complex dissociates (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar2 [plasma membrane] (Mus musculus)
    - G alpha (q) signalling events (Mus musculus)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar2 [plasma membrane] (Mus musculus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar2 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gq complex dissociates (Mus musculus)
        
        GPCRs that activate Gq/11 [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar2 [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Lysosphingolipid and LPA receptors (Mus musculus)
        
        LPA-binding receptors bind LPA (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar2 [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
        
        LPAR1,2,3,5 [plasma membrane] (Mus musculus)
        
        Lpar2 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9JL06

Gene Names

Lpar2

Reference Genes

BioGPS Gene:53978 Lpar2

ENSEMBL:ENSMUSG00000031861

ENSEMBL:ENSMUSG00000031861.17 Lpar2

KEGG Gene (Mus musculus):53978 Lpar2

Monarch:53978 Lpar2

NCBI Gene:53978 Lpar2

UCSC:Q9JL06 Lpar2

Reference Transcript

RefSeq:NM_020028.3 Lpar2

Other Identifiers

10572235

114162_at

1420576_at

1442291_at

17501748

4379472

4404157

4524732

4738140

4756114

4861021

4866339

5004531

5139343

5189423

5254866

53978

5531783

A_52_P460537

A_55_P1997591

GE117147

GE37663

GO:0004930

GO:0005737

GO:0005886

GO:0007165

GO:0007186

GO:0007189

GO:0009986

GO:0016020

GO:0019222

GO:0023052

GO:0030139

GO:0030165

GO:0031410

GO:0035025

GO:0043226

GO:0043410

GO:0048787

GO:0060089

GO:0070915

GO:0098978

ILMN_2661082

ILMN_2773817

mMC005809

mMC025626

Participates

as a member of

LPAR1,2,3,5 [plasma membrane] (Mus musculus)

Inferred From

LPAR2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_064412.2

Ensembl

ENSMUSG00000031861, ENSMUST00000034325, ENSMUSP00000128261, ENSMUSP00000034325, ENSMUST00000164890

PRO

Q9JL06

MGI

1858422

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