Reactome | Ltb4r [plasma membrane]

Ltb4r [plasma membrane]

Stable Identifier

R-MMU-416410

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

LTB4R, O88855

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (q) signalling events (Mus musculus)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        LTB4R,LTB4R2:LTB [plasma membrane] (Mus musculus)
        
        LTB4R,LTB4R2 [plasma membrane] (Mus musculus)
        
        Ltb4r [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        LTB4R,LTB4R2:LTB [plasma membrane] (Mus musculus)
        
        LTB4R,LTB4R2 [plasma membrane] (Mus musculus)
        
        Ltb4r [plasma membrane] (Mus musculus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        LTB4R,LTB4R2:LTB [plasma membrane] (Mus musculus)
        
        LTB4R,LTB4R2 [plasma membrane] (Mus musculus)
        
        Ltb4r [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        LTB4R,LTB4R2:LTB [plasma membrane] (Mus musculus)
        
        LTB4R,LTB4R2 [plasma membrane] (Mus musculus)
        
        Ltb4r [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gq complex dissociates (Mus musculus)
        
        GPCRs that activate Gq/11 [plasma membrane] (Mus musculus)
        
        LTB4R,LTB4R2 [plasma membrane] (Mus musculus)
        
        Ltb4r [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        LTB4R,LTB4R2:LTB [plasma membrane] (Mus musculus)
        
        LTB4R,LTB4R2 [plasma membrane] (Mus musculus)
        
        Ltb4r [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Eicosanoid ligand-binding receptors (Mus musculus)
        
        Leukotriene receptors (Mus musculus)
        
        BLT receptors can bind LTB4 (Mus musculus)
        
        LTB4R,LTB4R2 [plasma membrane] (Mus musculus)
        
        Ltb4r [plasma membrane] (Mus musculus)
        
        LTB4R,LTB4R2:LTB [plasma membrane] (Mus musculus)
        
        LTB4R,LTB4R2 [plasma membrane] (Mus musculus)
        
        Ltb4r [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:O88855

Gene Names

Ltb4r

Reference Genes

BioGPS Gene:16995 Ltb4r

CTD Gene:16995 Ltb4r

ENSEMBL:ENSMUSG00000046908

ENSEMBL:ENSMUSG00000046908.6 Ltb4r

KEGG Gene (Mus musculus):16995 Ltb4r

Monarch:16995 Ltb4r

NCBI Gene:16995 Ltb4r

UCSC:O88855 Ltb4r

Reference Transcript

RefSeq:NM_008519.2 Ltb4r

Other Identifiers

103266_at

10415392

1420407_at

16995

17300666

4402372

4798263

5283464

5517121

A_51_P109449

GE33958

GO:0001632

GO:0004930

GO:0004974

GO:0005886

GO:0007165

GO:0007186

GO:0007218

GO:0008528

GO:0016020

GO:0023052

GO:0060089

GO:0061737

ILMN_1220609

Msa.21459.0_s_at

mMC014179

Participates

as a member of

LTB4R,LTB4R2 [plasma membrane] (Mus musculus)

Inferred From

LTB4R [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_032545.1

ZINC - Substances

LT4R1_MOUSE

ZINC target

O88855

Ensembl

ENSMUSP00000051368, ENSMUST00000057569, ENSMUSG00000046908

PRO

O88855

MGI

1309472

ZINC - Predictions - Purchasable

LT4R1_MOUSE