Reactome | Htr5a [plasma membrane]

Htr5a [plasma membrane]

Stable Identifier

R-MMU-391007

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

HTR5A, P30966

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (i) signalling events (Mus musculus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        HTR1B,D,E,F,HTR5A:5HT [plasma membrane] (Mus musculus)
        
        HTR1B,D,E,F,HTR5A [plasma membrane] (Mus musculus)
        
        Htr5a [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        HTR1B,D,E,F,HTR5A:5HT [plasma membrane] (Mus musculus)
        
        HTR1B,D,E,F,HTR5A [plasma membrane] (Mus musculus)
        
        Htr5a [plasma membrane] (Mus musculus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        HTR1B,D,E,F,HTR5A:5HT [plasma membrane] (Mus musculus)
        
        HTR1B,D,E,F,HTR5A [plasma membrane] (Mus musculus)
        
        Htr5a [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        HTR1B,D,E,F,HTR5A:5HT [plasma membrane] (Mus musculus)
        
        HTR1B,D,E,F,HTR5A [plasma membrane] (Mus musculus)
        
        Htr5a [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gi complex dissociates (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        HTR1B,D,E,F,HTR5A:5HT [plasma membrane] (Mus musculus)
        
        HTR1B,D,E,F,HTR5A [plasma membrane] (Mus musculus)
        
        Htr5a [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        HTR1B,D,E,F,HTR5A:5HT [plasma membrane] (Mus musculus)
        
        HTR1B,D,E,F,HTR5A [plasma membrane] (Mus musculus)
        
        Htr5a [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Amine ligand-binding receptors (Mus musculus)
        
        Serotonin receptors (Mus musculus)
        
        HTR1 and 5A receptors can bind serotonin (Mus musculus)
        
        HTR1B,D,E,F,HTR5A [plasma membrane] (Mus musculus)
        
        Htr5a [plasma membrane] (Mus musculus)
        
        HTR1B,D,E,F,HTR5A:5HT [plasma membrane] (Mus musculus)
        
        HTR1B,D,E,F,HTR5A [plasma membrane] (Mus musculus)
        
        Htr5a [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P30966

Gene Names

Htr5a

Reference Genes

BioGPS Gene:15563 Htr5a

ENSEMBL:ENSMUSG00000039106

ENSEMBL:ENSMUSG00000039106.7 Htr5a

KEGG Gene (Mus musculus):15563 Htr5a

Monarch:15563 Htr5a

NCBI Gene:15563 Htr5a

UCSC:P30966 Htr5a

Reference Transcript

RefSeq:NM_008314.2 Htr5a

Other Identifiers

101152_at

10520355

1422207_at

1443276_at

15563

17435570

4449591

4882171

5051337

5169639

5188101

5259390

5266725

5351301

5478306

5503256

A_51_P151682

A_55_P2087345

GE34605

GO:0004930

GO:0004993

GO:0005886

GO:0007165

GO:0007186

GO:0007187

GO:0007189

GO:0007198

GO:0007268

GO:0016020

GO:0021766

GO:0023052

GO:0030425

GO:0030594

GO:0032355

GO:0043204

GO:0043226

GO:0048856

GO:0051378

GO:0060089

GO:0099634

ILMN_2681462

Z18278_s_at

mMC015332

Participates

as a member of

HTR1B,D,E,F,HTR5A [plasma membrane] (Mus musculus)

Inferred From

HTR5A [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_032340.2

ZINC - Investigational

5HT5A_MOUSE

ZINC - Metabolites

5HT5A_MOUSE

ZINC - World Drugs

5HT5A_MOUSE

ZINC - Substances

5HT5A_MOUSE

ZINC - Biogenic

5HT5A_MOUSE

Ensembl

ENSMUSP00000038884, ENSMUSG00000039106, ENSMUST00000036227

ZINC target

P30966

PRO

P30966

MGI

96283

ZINC - Predictions - Purchasable

5HT5A_MOUSE