Reactome | Chrm5 [plasma membrane]

Chrm5 [plasma membrane]

Stable Identifier

R-MMU-390678

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

CHRM5, Q920H4

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (q) signalling events (Mus musculus)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5:AcCho [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm5 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5:AcCho [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm5 [plasma membrane] (Mus musculus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5:AcCho [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm5 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5:AcCho [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm5 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gq complex dissociates (Mus musculus)
        
        GPCRs that activate Gq/11 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm5 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5:AcCho [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm5 [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Amine ligand-binding receptors (Mus musculus)
        
        Muscarinic acetylcholine receptors (Mus musculus)
        
        CHRM1,3,5 bind CHRM1,3,5 antagonists (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm5 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5:CHRM1,3,5 antagonists [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm5 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 bind acetylcholine (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm5 [plasma membrane] (Mus musculus)
        
        CHRM1,3,5:AcCho [plasma membrane] (Mus musculus)
        
        CHRM1,3,5 [plasma membrane] (Mus musculus)
        
        Chrm5 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q920H4

Gene Names

Chrm5

Reference Genes

BioGPS Gene:213788 Chrm5

ENSEMBL:ENSMUSG00000074939

ENSEMBL:ENSMUSG00000074939.4 Chrm5

KEGG Gene (Mus musculus):213788 Chrm5

Monarch:213788 Chrm5

NCBI Gene:213788 Chrm5

UCSC:Q920H4 Chrm5

Reference Transcript

Other Identifiers

10485836

111637_at

17389335

213788

4450452

4538648

4914026

4948717

5107187

A_51_P409677

A_55_P2055247

GE1524182

GO:0001696

GO:0004930

GO:0004993

GO:0005215

GO:0005886

GO:0006629

GO:0007165

GO:0007186

GO:0007187

GO:0007197

GO:0007268

GO:0015872

GO:0016020

GO:0016907

GO:0016934

GO:0019226

GO:0022600

GO:0023052

GO:0030425

GO:0045202

GO:0045211

GO:0050877

GO:0055085

GO:0060079

GO:0060089

GO:0060304

GO:0098664

GO:1902476

ILMN_2661904

Msa.6734.0_s_at

mMC026432

Participates

as a member of

CHRM1,3,5 [plasma membrane] (Mus musculus)

Inferred From

CHRM5 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_991352.2, XP_006499162.1

Ensembl

ENSMUSG00000074939, ENSMUST00000099589, ENSMUSP00000097185

PRO

Q920H4

MGI

109248