Reactome | Npffr2 [plasma membrane]

Npffr2 [plasma membrane]

Stable Identifier

R-MMU-389476

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

NPFFR2, Q924H0

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (q) signalling events (Mus musculus)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2 [plasma membrane] (Mus musculus)
        
        Npffr2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2 [plasma membrane] (Mus musculus)
        
        Npffr2 [plasma membrane] (Mus musculus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2 [plasma membrane] (Mus musculus)
        
        Npffr2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2 [plasma membrane] (Mus musculus)
        
        Npffr2 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gq complex dissociates (Mus musculus)
        
        GPCRs that activate Gq/11 [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2 [plasma membrane] (Mus musculus)
        
        Npffr2 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2 [plasma membrane] (Mus musculus)
        
        Npffr2 [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Peptide ligand-binding receptors (Mus musculus)
        
        Orexin and neuropeptides FF and QRFP bind to their respective receptors (Mus musculus)
        
        Two NPFF receptors can bind neuropeptide FF (Mus musculus)
        
        NPFFR1,NPFFR2 [plasma membrane] (Mus musculus)
        
        Npffr2 [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2 [plasma membrane] (Mus musculus)
        
        Npffr2 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q924H0

Gene Names

Npffr2

Reference Genes

BioGPS Gene:104443 Npffr2

ENSEMBL:ENSMUSG00000035528

KEGG:mmu:104443 Npffr2

Monarch:104443 Npffr2

NCBI Gene:104443 Npffr2

UCSC:Q924H0 Npffr2

Reference Transcript

Other Identifiers

104443

10523048

1422214_at

17438869

4419130

4658723

5206083

5276097

5500577

5603744

5610959

A_52_P356128

GE126704

GO:0004930

GO:0005856

GO:0005886

GO:0007186

GO:0007218

GO:0008188

GO:0015629

GO:0016020

GO:0031628

GO:0032870

GO:0042277

GO:0043226

GO:0043408

GO:0045761

GO:0060089

GO:2000479

ILMN_1227800

ILMN_2723735

ILMN_3067357

ILMN_3145557

mMC004071

Participates

as a member of

NPFFR1,NPFFR2 [plasma membrane] (Mus musculus)

Inferred From

NPFFR2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_017176078.1, NP_573455.2

ENSEMBL

ENSMUSP00000040033, ENSMUSG00000035528, ENSMUST00000048557

PRO

Q924H0

GlyGen

Q924H0

MGI

1860130