Reactome | Npffr1 [plasma membrane]

Npffr1 [plasma membrane]

Stable Identifier

R-MMU-389429

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

NPFFR1, E9Q468

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (q) signalling events (Mus musculus)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2 [plasma membrane] (Mus musculus)
        
        Npffr1 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2 [plasma membrane] (Mus musculus)
        
        Npffr1 [plasma membrane] (Mus musculus)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2 [plasma membrane] (Mus musculus)
        
        Npffr1 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2 [plasma membrane] (Mus musculus)
        
        Npffr1 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gq complex dissociates (Mus musculus)
        
        GPCRs that activate Gq/11 [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2 [plasma membrane] (Mus musculus)
        
        Npffr1 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2 [plasma membrane] (Mus musculus)
        
        Npffr1 [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Peptide ligand-binding receptors (Mus musculus)
        
        Orexin and neuropeptides FF and QRFP bind to their respective receptors (Mus musculus)
        
        Two NPFF receptors can bind neuropeptide FF (Mus musculus)
        
        NPFFR1,NPFFR2 [plasma membrane] (Mus musculus)
        
        Npffr1 [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Mus musculus)
        
        NPFFR1,NPFFR2 [plasma membrane] (Mus musculus)
        
        Npffr1 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:E9Q468

Gene Names

Npffr1

Reference Genes

BioGPS Gene:237362 Npffr1

ENSEMBL:ENSMUSG00000020090

KEGG:mmu:237362 Npffr1

Monarch:237362 Npffr1

NCBI Gene:237362 Npffr1

UCSC:E9Q468 Npffr1

Reference Transcript

RefSeq:NM_001177511.1 Npffr1

Other Identifiers

10363492

17233716

237362

4376995

4475512

4538992

4540849

4773386

5024546

5293974

5328965

5537129

A_52_P133626

A_55_P2152369

GE1457552

GO:0004930

GO:0005886

GO:0005929

GO:0007186

GO:0007218

GO:0008188

GO:0016020

GO:0032870

GO:0042277

GO:0043226

GO:0060089

ILMN_2533797

Participates

as a member of

NPFFR1,NPFFR2 [plasma membrane] (Mus musculus)

Inferred From

NPFFR1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001170982.1

ENSEMBL

ENSMUSG00000020090, ENSMUST00000020287, ENSMUSP00000020287

MGI

2685082