Reactome | Scmh1 [nucleoplasm]

Scmh1 [nucleoplasm]

Stable Identifier

R-MMU-389122

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

SCMH1-2, Q8K214

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - Generic Transcription Pathway (Mus musculus)
    - Transcriptional regulation by RUNX1 (Mus musculus)
      - RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known (Mus musculus)
        
        RUNX1 binds PRC1 complexes (Mus musculus)
        
        (PRC1.4,PRC1.5) [nucleoplasm] (Mus musculus)
        
        PRC1.4 [nucleoplasm] (Mus musculus)
        
        Scmh1 [nucleoplasm] (Mus musculus)
        
        RUNX1:CBFB:(PRC1.4,PRC1.5) [nucleoplasm] (Mus musculus)
        
        (PRC1.4,PRC1.5) [nucleoplasm] (Mus musculus)
        
        PRC1.4 [nucleoplasm] (Mus musculus)
        
        Scmh1 [nucleoplasm] (Mus musculus)

Signal Transduction (Mus musculus)

- Intracellular signaling by second messengers (Mus musculus)
  - PIP3 activates AKT signaling (Mus musculus)
    - PTEN Regulation (Mus musculus)
      - Regulation of PTEN gene transcription (Mus musculus)
        
        MECOM (EVI1) recruits polycomb repressor complexes (PRCs) to the PTEN gene promoter (Mus musculus)
        
        MECOM:(PRC1.4,PRC2 (EZH2) core):PTEN gene [nucleoplasm] (Mus musculus)
        
        MECOM:(PRC1.4,PRC2 (EZH2) core) [nucleoplasm] (Mus musculus)
        
        PRC1.4,PRC2 (EZH2) core [nucleoplasm] (Mus musculus)
        
        PRC1.4 [nucleoplasm] (Mus musculus)
        
        Scmh1 [nucleoplasm] (Mus musculus)
        
        PRC1.4,PRC2 (EZH2) core [nucleoplasm] (Mus musculus)
        
        PRC1.4 [nucleoplasm] (Mus musculus)
        
        Scmh1 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:Q8K214

Gene Names

Scmh1

Reference Genes

BioGPS Gene:29871 Scmh1

ENSEMBL:ENSMUSG00000000085

KEGG Gene (Mus musculus):29871 Scmh1

Monarch:29871 Scmh1

NCBI Gene:29871 Scmh1

UCSC:Q8K214 Scmh1

Reference Transcript

Other Identifiers

103399_at

10507699

1426241_a_at

17417988

29871

4314072

4439838

4450872

4621541

4636737

4700435

4771117

4817492

4823301

4827714

4836228

4968045

5141370

5164402

5187579

5243692

5316254

5381994

5403781

5440109

5477198

5496606

5523214

5535962

A_52_P31246

A_55_P2030736

GE36346

GO:0000003

GO:0003674

GO:0003682

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005694

GO:0006338

GO:0006355

GO:0007275

GO:0007283

GO:0008150

GO:0009058

GO:0009952

GO:0010369

GO:0016458

GO:0034641

GO:0042393

GO:0043226

GO:0045892

GO:0048856

GO:0051276

ILMN_1230766

ILMN_2474640

ILMN_2720786

mMC006978

mMR028430

Participant Of

hasComponent

Inferred From

SCMH1-2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_017175741.1, NP_038911.1, NP_001153102.1, XP_017175742.1, XP_011238853.1

Ensembl

ENSMUSP00000069813, ENSMUSP00000101908, ENSMUSP00000000087, ENSMUST00000106301, ENSMUST00000064991, ENSMUST00000000087, ENSMUST00000106298, ENSMUSG00000000085, ENSMUSP00000101905

PRO

Q8K214

MGI

1352762

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O88513	2	Gmnn [cytosol] (R-MMU-68534) Gmnn [nucleoplasm] (R-MMU-113554)	0.508	2