Reactome | Mc2r [plasma membrane]

Mc2r [plasma membrane]

Stable Identifier

R-MMU-388600

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

MC2R, Q64326

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (s) signalling events (Mus musculus)
      - Liganded Gs-activating GPCR acts as a GEF for Gs (Mus musculus)
        
        GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Mus musculus)
        
        POMC(138-176):MC2R [plasma membrane] (Mus musculus)
        
        Mc2r [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Mus musculus)
        
        POMC(138-176):MC2R [plasma membrane] (Mus musculus)
        
        Mc2r [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Peptide ligand-binding receptors (Mus musculus)
        
        POMC(138-176) binds MC2R (Mus musculus)
        
        Mc2r [plasma membrane] (Mus musculus)
        
        POMC(138-176):MC2R [plasma membrane] (Mus musculus)
        
        Mc2r [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q64326

Gene Names

Mc2r

Reference Genes

BioGPS Gene:17200 Mc2r

ENSEMBL:ENSMUSG00000045569

ENSEMBL:ENSMUSG00000045569.8 Mc2r

KEGG Gene (Mus musculus):17200 Mc2r

Monarch:17200 Mc2r

NCBI Gene:17200 Mc2r

UCSC:Q64326 Mc2r

Reference Transcript

Other Identifiers

10459611

135817_at

1422926_at

17200

17355264

4583412

4958063

4967905

5145058

5238007

5360332

5601860

92429_at

A_51_P268687

A_55_P2031058

A_55_P2741392

GE118146

GO:0001890

GO:0004930

GO:0004977

GO:0004978

GO:0005737

GO:0005886

GO:0007165

GO:0007186

GO:0007189

GO:0007218

GO:0016020

GO:0019222

GO:0023052

GO:0048856

GO:0060089

ILMN_2595350

Msa.1831.0_at

mMC006839

Participates

as an input of

POMC(138-176) binds MC2R (Mus musculus)

as a component of

POMC(138-176):MC2R [plasma membrane] (Mus musculus)

Inferred From

MC2R [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001258645.1, NP_001258646.1, NP_032586.1, NP_001288301.1

Ensembl

ENSMUSP00000058691, ENSMUST00000052347, ENSMUSG00000045569

ZINC target

Q64326

PRO

Q64326

MGI

96928

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