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Ckap5 [cytosol]
Stable Identifier
R-MMU-377729
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
CKAP5, A2AGT5
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Cell Cycle Checkpoints (Mus musculus)
Mitotic Spindle Checkpoint (Mus musculus)
Amplification of signal from the kinetochores (Mus musculus)
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (Mus musculus)
MAD2 associates with the Mad1 kinetochore complex (Mus musculus)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Mus musculus)
Mad1:kinetochore complex [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Mad1:kinetochore complex [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
MAD2 converted to an inhibitory state via interaction with Mad1 (Mus musculus)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Mus musculus)
Mad1:kinetochore complex [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Mad1 binds kinetochore (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Mad1:kinetochore complex [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Release of activated MAD2 from kinetochores (Mus musculus)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Mus musculus)
Mad1:kinetochore complex [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Mad1:kinetochore complex [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
M Phase (Mus musculus)
Mitotic Metaphase and Anaphase (Mus musculus)
Mitotic Anaphase (Mus musculus)
Separation of Sister Chromatids (Mus musculus)
ESPL1 (Separase) cleaves centromeric cohesin (Mus musculus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Separation of sister chromatids (Mus musculus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Sister Centromere:Kinetochore:Microtubules [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Mitotic Prometaphase (Mus musculus)
EML4 and NUDC in mitotic spindle formation (Mus musculus)
EML4 recruits NUDC to mitotic spindle (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Kinetochore capture of astral microtubules (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Recruitment of NuMA to mitotic centrosomes (Mus musculus)
Association of NuMA with microtubules (Mus musculus)
Mature centrosome enriched in gamma-TURC:p-T2055-NUMA1 homodimer [cytosol] (Mus musculus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
p-T2055-NUMA1 homodimer:Mature centrosome:nucleated microtubules [cytosol] (Mus musculus)
Mature centrosome:nucleated microtubules [cytosol] (Mus musculus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Translocation of NuMA to the centrosomes (Mus musculus)
Mature centrosome enriched in gamma-TURC:p-T2055-NUMA1 homodimer [cytosol] (Mus musculus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Resolution of Sister Chromatid Cohesion (Mus musculus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Mus musculus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Mus musculus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Kinetochore assembly (Mus musculus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Mus musculus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
PP2A-B56 dephosphorylates centromeric cohesin (Mus musculus)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Phosphorylation of cohesin by PLK1 at centromeres (Mus musculus)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Mitotic G2-G2/M phases (Mus musculus)
G2/M Transition (Mus musculus)
AURKA Activation by TPX2 (Mus musculus)
TPX2 binds AURKA at centrosomes (Mus musculus)
Centrosome:AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Centrosome:AURKA:TPX2:HMMR [cytosol] (Mus musculus)
Centrosome:AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
TPX2 promotes AURKA autophosphorylation (Mus musculus)
Centrosome:AURKA:TPX2:HMMR [cytosol] (Mus musculus)
Centrosome:AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Centrosome:p-T288-AURKA:TPX2:HMMR [cytosol] (Mus musculus)
Centrosome:p-T288-AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Centrosome maturation (Mus musculus)
Loss of proteins required for interphase microtubule organization from the centrosome (Mus musculus)
Loss of C-Nap-1 from centrosomes (Mus musculus)
cNAP-1 depleted centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Loss of Nlp from mitotic centrosomes (Mus musculus)
Dissociation of Phospho-Nlp from the centrosome (Mus musculus)
Nlp-depleted centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
centrosome containing phosphorylated Nlp [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Plk1-mediated phosphorylation of Nlp (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
centrosome containing phosphorylated Nlp [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Recruitment of mitotic centrosome proteins and complexes (Mus musculus)
Recruitment of CDK11p58 to the centrosomes (Mus musculus)
Centrosomes containing recruited CDK11p58 [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Recruitment of Plk1 to centrosomes (Mus musculus)
Centrosome associated Plk1 [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome (Mus musculus)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Regulation of PLK1 Activity at G2/M Transition (Mus musculus)
AJUBA binds centrosome-associated AURKA (Mus musculus)
Centrosome:AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Centrosome:AURKA:AJUBA [cytosol] (Mus musculus)
Centrosome:AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
AJUBA facilitates AURKA autophosphorylation (Mus musculus)
Centrosome:AURKA:AJUBA [cytosol] (Mus musculus)
Centrosome:AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Centrosome:p-T288-AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
AURKA phosphorylates PLK1 (Mus musculus)
Centrosome:p-T288-AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol] (Mus musculus)
Centrosome:p-T288-AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
BORA binds PLK1 and AURKA (Mus musculus)
Centrosome:p-T288-AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol] (Mus musculus)
Centrosome:p-T288-AURKA [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Organelle biogenesis and maintenance (Mus musculus)
Cilium Assembly (Mus musculus)
Anchoring of the basal body to the plasma membrane (Mus musculus)
C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Mus musculus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
mother centriole:C2CD3 [cytosol] (Mus musculus)
mother centriole [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
mother centriole:C2CD3 [cytosol] (Mus musculus)
mother centriole [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
C2CD3 binds the mother centriole (Mus musculus)
mother centriole [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
mother centriole:C2CD3 [cytosol] (Mus musculus)
mother centriole [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Mus musculus)
basal body:transition zone proteins [cytosol] (Mus musculus)
basal body [cytosol] (Mus musculus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Mus musculus)
basal body:transition zone proteins [cytosol] (Mus musculus)
basal body [cytosol] (Mus musculus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
CP110 and CEP97 dissociate from the centriole (Mus musculus)
basal body [cytosol] (Mus musculus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Mus musculus)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
mother centriole:C2CD3 [cytosol] (Mus musculus)
mother centriole [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
MARK4 binds ODF2 in the centriole (Mus musculus)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
mother centriole:C2CD3 [cytosol] (Mus musculus)
mother centriole [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Mus musculus)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
mother centriole:C2CD3 [cytosol] (Mus musculus)
mother centriole [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
RAB3IP stimulates nucleotide exchange on RAB8A (Mus musculus)
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Mus musculus)
basal body:transition zone proteins [cytosol] (Mus musculus)
basal body [cytosol] (Mus musculus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Recruitment of transition zone proteins (Mus musculus)
basal body [cytosol] (Mus musculus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
basal body:transition zone proteins [cytosol] (Mus musculus)
basal body [cytosol] (Mus musculus)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
The distal appendage proteins recruit TTBK2 (Mus musculus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
mother centriole:C2CD3 [cytosol] (Mus musculus)
mother centriole [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
mother centriole:C2CD3 [cytosol] (Mus musculus)
mother centriole [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase Effectors (Mus musculus)
RHO GTPases Activate Formins (Mus musculus)
AURKB phosphorylates DIAPH2-2 at kinetochores (Mus musculus)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
CDC42:GTP recruits DIAPH2-2 to kinetochores (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Ckap5 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:A2AGT5
Gene Names
Ckap5
Reference Genes
BioGPS Gene:75786 Ckap5
ENSEMBL:ENSMUSG00000040549
KEGG Gene (Mus musculus):75786 Ckap5
Monarch:75786 Ckap5
NCBI Gene:75786 Ckap5
UCSC:A2AGT5 Ckap5
Reference Transcript
RefSeq:NM_029437.2 Ckap5
Participates
as a component of
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Mus musculus)
mother centriole [cytosol] (Mus musculus)
Nlp-depleted centrosome [cytosol] (Mus musculus)
centrosome containing phosphorylated Nlp [cytosol] (Mus musculus)
cNAP-1 depleted centrosome [cytosol] (Mus musculus)
centrosome [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
Inferred From
CKAP5 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_083713.2
PRO
A2AGT5
MGI
1923036
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Y6A5 TACC3
1
TACC3 [cytosol]
(R-HSA-2160956)
0.564
2
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