Reactome | Cxcl10 [extracellular region]

Cxcl10 [extracellular region]

Stable Identifier

R-MMU-373853

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

extracellular region

Synonyms

CXCL10(22-98), P17515

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (i) signalling events (Mus musculus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        CXCR3:CXCR3 ligands [plasma membrane] (Mus musculus)
        
        CXCR3 ligands [extracellular region] (Mus musculus)
        
        Cxcl10 [extracellular region] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        CXCR3:CXCR3 ligands [plasma membrane] (Mus musculus)
        
        CXCR3 ligands [extracellular region] (Mus musculus)
        
        Cxcl10 [extracellular region] (Mus musculus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        CXCR3:CXCR3 ligands [plasma membrane] (Mus musculus)
        
        CXCR3 ligands [extracellular region] (Mus musculus)
        
        Cxcl10 [extracellular region] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        CXCR3:CXCR3 ligands [plasma membrane] (Mus musculus)
        
        CXCR3 ligands [extracellular region] (Mus musculus)
        
        Cxcl10 [extracellular region] (Mus musculus)
      - The Ligand:GPCR:Gi complex dissociates (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        CXCR3:CXCR3 ligands [plasma membrane] (Mus musculus)
        
        CXCR3 ligands [extracellular region] (Mus musculus)
        
        Cxcl10 [extracellular region] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        CXCR3:CXCR3 ligands [plasma membrane] (Mus musculus)
        
        CXCR3 ligands [extracellular region] (Mus musculus)
        
        Cxcl10 [extracellular region] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Peptide ligand-binding receptors (Mus musculus)
        
        Chemokine receptors bind chemokines (Mus musculus)
        
        Receptor CXCR3 binds ligands CXCL9 to 11 (Mus musculus)
        
        CXCR3 ligands [extracellular region] (Mus musculus)
        
        Cxcl10 [extracellular region] (Mus musculus)
        
        CXCR3:CXCR3 ligands [plasma membrane] (Mus musculus)
        
        CXCR3 ligands [extracellular region] (Mus musculus)
        
        Cxcl10 [extracellular region] (Mus musculus)

External Reference Information

External Reference

UniProt:P17515

Gene Names

Cxcl10

Reference Genes

BioGPS Gene:15945 Cxcl10

ENSEMBL:ENSMUSG00000034855

ENSEMBL:ENSMUSG00000034855.14 Cxcl10

KEGG Gene (Mus musculus):15945 Cxcl10

Monarch:15945 Cxcl10

NCBI Gene:15945 Cxcl10

UCSC:P17515 Cxcl10

Reference Transcript

RefSeq:NM_021274.2 Cxcl10

Other Identifiers

10531415

1418930_at

15945

17449718

4484123

4632329

4665730

4908082

5082230

5285101

5538705

93858_at

A_51_P432641

A_55_P2016462

GE37868

GO:0002376

GO:0002690

GO:0005125

GO:0005576

GO:0005615

GO:0005886

GO:0006935

GO:0006952

GO:0006954

GO:0006955

GO:0007186

GO:0007189

GO:0008009

GO:0008201

GO:0008284

GO:0009617

GO:0009897

GO:0010818

GO:0010819

GO:0012501

GO:0016525

GO:0023052

GO:0030154

GO:0030335

GO:0030593

GO:0031640

GO:0042056

GO:0042118

GO:0042127

GO:0042981

GO:0045236

GO:0045662

GO:0048018

GO:0048248

GO:0048856

GO:0048870

GO:0050896

GO:0050918

GO:0051281

GO:0051607

GO:0055065

GO:0055085

GO:0061844

GO:0070098

GO:0071222

GO:0090026

GO:0097398

GO:0098542

GO:0098586

GO:0098772

GO:0140374

GO:1901509

GO:1901740

GO:2000406

ILMN_1214419

ILMN_3142803

m33266_s_at

mMC013715

Participates

as a member of

CXCR3 ligands [extracellular region] (Mus musculus)

Inferred From

CXCL10(22-98) [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_067249.1

Ensembl

ENSMUSG00000034855, ENSMUST00000038816, ENSMUSP00000047646

PRO

P17515

MGI

1352450

PDB

2R3Z

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