Reactome | Tas2r120 [plasma membrane]

Tas2r120 [plasma membrane]

Stable Identifier

R-MMU-3299625

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

TAS2R19, Q7M721

Locations in the PathwayBrowser

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Sensory Perception (Mus musculus)

- Sensory perception of taste (Mus musculus)
  - Sensory perception of sweet, bitter, and umami (glutamate) taste (Mus musculus)
    - Bitter compound binds bitter taste receptor (TAS2R) (Mus musculus)
      - TAS2R:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Mus musculus)
        
        TAS2R (non-orphan) [plasma membrane] (Mus musculus)
        
        Homologues of TAS2R19 [plasma membrane] (Mus musculus)
        
        Tas2r120 [plasma membrane] (Mus musculus)
      - TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Mus musculus)
        
        TAS2R (non-orphan):ligand [plasma membrane] (Mus musculus)
        
        TAS2R50:ligand [plasma membrane] (Mus musculus)
        
        Homologues of TAS2R19 [plasma membrane] (Mus musculus)
        
        Tas2r120 [plasma membrane] (Mus musculus)

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (i) signalling events (Mus musculus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Homologues of TAS2R19 [plasma membrane] (Mus musculus)
        
        Tas2r120 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Homologues of TAS2R19 [plasma membrane] (Mus musculus)
        
        Tas2r120 [plasma membrane] (Mus musculus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Homologues of TAS2R19 [plasma membrane] (Mus musculus)
        
        Tas2r120 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Homologues of TAS2R19 [plasma membrane] (Mus musculus)
        
        Tas2r120 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gi complex dissociates (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Homologues of TAS2R19 [plasma membrane] (Mus musculus)
        
        Tas2r120 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Homologues of TAS2R19 [plasma membrane] (Mus musculus)
        
        Tas2r120 [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Mus musculus)
      - T2Rs bind bitter-tasting compounds (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Homologues of TAS2R19 [plasma membrane] (Mus musculus)
        
        Tas2r120 [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Homologues of TAS2R19 [plasma membrane] (Mus musculus)
        
        Tas2r120 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q7M721

Gene Names

Tas2r120

Reference Genes

BioGPS Gene:387348 Tas2r120

CTD Gene:387348 Tas2r120

ENSEMBL:ENSMUSG00000059382

ENSEMBL:ENSMUSG00000059382.3 Tas2r120

KEGG Gene (Mus musculus):387348 Tas2r120

Monarch:387348 Tas2r120

NCBI Gene:387348 Tas2r120

UCSC:Q7M721 Tas2r120

Reference Transcript

RefSeq:NM_207023.1 Tas2r120

Other Identifiers

10542241

17463626

387348

4656096

4981851

5106711

A_55_P1960221

GO:0001580

GO:0004930

GO:0005929

GO:0007165

GO:0007186

GO:0008527

GO:0016020

GO:0023052

GO:0031514

GO:0033038

GO:0043226

GO:0050877

GO:0050896

GO:0050909

GO:0050912

GO:0060089

ILMN_1232017

ILMN_2783020

mMC021370

Participates

as a member of

Homologues of TAS2R19 [plasma membrane] (Mus musculus)

Other forms of this molecule

Tas2r120 [plasma membrane]

Inferred From

TAS2R45 [plasma membrane] (Homo sapiens)

TAS2R19 [plasma membrane] (Homo sapiens)

TAS2R50 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_996906.1

Ensembl

ENSMUSG00000059382, ENSMUSP00000071626, ENSMUST00000071707

PRO

Q7M721

MGI

2681256

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