Reactome | Tas2r39 [plasma membrane]

Tas2r39 [plasma membrane]

Stable Identifier

R-MMU-3299609

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

TAS2R39, Q7TQA5

Locations in the PathwayBrowser

Expand all

Sensory Perception (Mus musculus)

- Sensory perception of taste (Mus musculus)
  - Sensory perception of sweet, bitter, and umami (glutamate) taste (Mus musculus)
    - Bitter compound binds bitter taste receptor (TAS2R) (Mus musculus)
      - TAS2R:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Mus musculus)
        
        TAS2R (non-orphan) [plasma membrane] (Mus musculus)
        
        Tas2r39 [plasma membrane] (Mus musculus)
      - TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Mus musculus)
        
        TAS2R (non-orphan):ligand [plasma membrane] (Mus musculus)
        
        TAS2R39:ligand [plasma membrane] (Mus musculus)
        
        Tas2r39 [plasma membrane] (Mus musculus)

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (i) signalling events (Mus musculus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Tas2r39 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Tas2r39 [plasma membrane] (Mus musculus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Tas2r39 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Tas2r39 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gi complex dissociates (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Tas2r39 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Tas2r39 [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Mus musculus)
      - T2Rs bind bitter-tasting compounds (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Tas2r39 [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Tas2r39 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q7TQA5

Gene Names

Tas2r39

Reference Genes

BioGPS Gene:353148 Tas2r39

CTD Gene:353148 Tas2r39

ENSEMBL:ENSMUSG00000047102

ENSEMBL:ENSMUSG00000047102.5 Tas2r39

KEGG Gene (Mus musculus):353148 Tas2r39

Monarch:353148 Tas2r39

NCBI Gene:353148 Tas2r39

UCSC:Q7TQA5 Tas2r39

Reference Transcript

RefSeq:NM_181275.1 Tas2r39

Other Identifiers

10537707

17457872

353148

4633320

4897298

5096396

5369689

5378700

A_52_P254141

A_55_P2060657

GE1387426

GO:0001580

GO:0004930

GO:0007165

GO:0007186

GO:0008527

GO:0016020

GO:0023052

GO:0033038

GO:0050877

GO:0050896

GO:0050909

GO:0050912

GO:0060089

ILMN_1221481

mMC013396

Participates

as a member of

as a component of

TAS2R39:ligand [plasma membrane] (Mus musculus)

Inferred From

TAS2R39 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_851792.1

Ensembl

ENSMUST00000057686, ENSMUSP00000062919, ENSMUSG00000047102

PRO

Q7TQA5

MGI

2681308