Reactome | Tas2r40 [plasma membrane]

Tas2r40 [plasma membrane]

Stable Identifier

R-MMU-3299608

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

TAS2R40, Q7TQB8

Locations in the PathwayBrowser

Expand all

Sensory Perception (Mus musculus)

- Sensory perception of taste (Mus musculus)
  - Sensory perception of sweet, bitter, and umami (glutamate) taste (Mus musculus)
    - Bitter compound binds bitter taste receptor (TAS2R) (Mus musculus)
      - TAS2R:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Mus musculus)
        
        TAS2R (non-orphan) [plasma membrane] (Mus musculus)
        
        Tas2r40 [plasma membrane] (Mus musculus)
      - TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Mus musculus)
        
        TAS2R (non-orphan):ligand [plasma membrane] (Mus musculus)
        
        TAS2R40:ligand [plasma membrane] (Mus musculus)
        
        Tas2r40 [plasma membrane] (Mus musculus)

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (i) signalling events (Mus musculus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Tas2r40 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Tas2r40 [plasma membrane] (Mus musculus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Tas2r40 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Tas2r40 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gi complex dissociates (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Tas2r40 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Tas2r40 [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Mus musculus)
      - T2Rs bind bitter-tasting compounds (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Tas2r40 [plasma membrane] (Mus musculus)
        
        TAS2Rs:Bitter-tasting compounds [plasma membrane] (Mus musculus)
        
        TAS2Rs [plasma membrane] (Mus musculus)
        
        Tas2r40 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q7TQB8

Gene Names

Tas2r40

Reference Genes

BioGPS Gene:387515 Tas2r40

CTD Gene:387515 Tas2r40

ENSEMBL:ENSMUSG00000051917

ENSEMBL:ENSMUSG00000051917.4 Tas2r40

KEGG Gene (Mus musculus):387515 Tas2r40

Monarch:387515 Tas2r40

NCBI Gene:387515 Tas2r40

UCSC:Q7TQB8 Tas2r40

Reference Transcript

RefSeq:NM_001001453.1 Tas2r40

Other Identifiers

10537710

17457874

387515

4490491

5060349

5384653

A_55_P2004646

GO:0001580

GO:0004930

GO:0007165

GO:0007186

GO:0008527

GO:0016020

GO:0023052

GO:0033038

GO:0050877

GO:0050896

GO:0050909

GO:0050912

GO:0060089

ILMN_3160931

Participates

as a member of

as a component of

TAS2R40:ligand [plasma membrane] (Mus musculus)

Inferred From

TAS2R40 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001001453.1

Ensembl

ENSMUST00000063489, ENSMUSG00000051917, ENSMUSP00000067734

PRO

Q7TQB8

MGI

2681312