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RAD17 [nucleoplasm]
Stable Identifier
R-MMU-3008665
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
nucleoplasm
Synonyms
Q6NXW6
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Cell Cycle Checkpoints (Mus musculus)
G2/M Checkpoints (Mus musculus)
Activation of ATR in response to replication stress (Mus musculus)
Recruitment of Rad17-RFC complex to DNA (Mus musculus)
RAD17:RFC [nucleoplasm] (Mus musculus)
RAD17 [nucleoplasm] (Mus musculus)
Rad17-RFC complex bound to DNA [nucleoplasm] (Mus musculus)
RAD17:RFC [nucleoplasm] (Mus musculus)
RAD17 [nucleoplasm] (Mus musculus)
Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Mus musculus)
Rad17-RFC complex bound to DNA [nucleoplasm] (Mus musculus)
RAD17:RFC [nucleoplasm] (Mus musculus)
RAD17 [nucleoplasm] (Mus musculus)
Rad9-Hus1-Rad1 bound to DNA [nucleoplasm] (Mus musculus)
Rad17-RFC complex bound to DNA [nucleoplasm] (Mus musculus)
RAD17:RFC [nucleoplasm] (Mus musculus)
RAD17 [nucleoplasm] (Mus musculus)
G2/M DNA damage checkpoint (Mus musculus)
ATR phosphorylates TP53 (Mus musculus)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
RAD17:RFC [nucleoplasm] (Mus musculus)
RAD17 [nucleoplasm] (Mus musculus)
DNA Repair (Mus musculus)
DNA Double-Strand Break Repair (Mus musculus)
Homology Directed Repair (Mus musculus)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Mus musculus)
HDR through Single Strand Annealing (SSA) (Mus musculus)
Association of RAD51 with RAD52:DNA double-strand break ends (Mus musculus)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
RAD17:RFC [nucleoplasm] (Mus musculus)
RAD17 [nucleoplasm] (Mus musculus)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
RAD17:RFC [nucleoplasm] (Mus musculus)
RAD17 [nucleoplasm] (Mus musculus)
Association of RAD52 with the RPA complex at resected DNA DSBs (Mus musculus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
RAD17:RFC [nucleoplasm] (Mus musculus)
RAD17 [nucleoplasm] (Mus musculus)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
RAD17:RFC [nucleoplasm] (Mus musculus)
RAD17 [nucleoplasm] (Mus musculus)
ERCC1:XPF cleaves flaps generated by SSA (Mus musculus)
RAD17:RFC [nucleoplasm] (Mus musculus)
RAD17 [nucleoplasm] (Mus musculus)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
ATR:ATRIP:p-RPA:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
RAD17:RFC [nucleoplasm] (Mus musculus)
RAD17 [nucleoplasm] (Mus musculus)
RAD52 promotes single strand annealing at resected DNA DSBs (Mus musculus)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
RAD17:RFC [nucleoplasm] (Mus musculus)
RAD17 [nucleoplasm] (Mus musculus)
RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
ATR:ATRIP:p-RPA:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
RAD17:RFC [nucleoplasm] (Mus musculus)
RAD17 [nucleoplasm] (Mus musculus)
Processing of DNA double-strand break ends (Mus musculus)
ATR activation at DNA DSBs (Mus musculus)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
RAD17:RFC [nucleoplasm] (Mus musculus)
RAD17 [nucleoplasm] (Mus musculus)
RAD17:RFC [nucleoplasm] (Mus musculus)
RAD17 [nucleoplasm] (Mus musculus)
ATR phosphorylates RPA2 (Mus musculus)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
RAD17:RFC [nucleoplasm] (Mus musculus)
RAD17 [nucleoplasm] (Mus musculus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
RAD17:RFC [nucleoplasm] (Mus musculus)
RAD17 [nucleoplasm] (Mus musculus)
Activation of CHEK1 at resected DNA DSBs (Mus musculus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
RAD17:RFC [nucleoplasm] (Mus musculus)
RAD17 [nucleoplasm] (Mus musculus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Mus musculus)
RAD17:RFC [nucleoplasm] (Mus musculus)
RAD17 [nucleoplasm] (Mus musculus)
CHEK1 is recruited to resected DNA DSBs (Mus musculus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
RAD17:RFC [nucleoplasm] (Mus musculus)
RAD17 [nucleoplasm] (Mus musculus)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Mus musculus)
RAD17:RFC [nucleoplasm] (Mus musculus)
RAD17 [nucleoplasm] (Mus musculus)
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional Regulation by TP53 (Mus musculus)
Regulation of TP53 Activity (Mus musculus)
Regulation of TP53 Activity through Phosphorylation (Mus musculus)
ATR phosphorylates TP53 (Mus musculus)
ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Mus musculus)
RAD17:RFC [nucleoplasm] (Mus musculus)
RAD17 [nucleoplasm] (Mus musculus)
External Reference Information
External Reference
UniProt:Q6NXW6
Reference Genes
BioGPS Gene:19356
ENSEMBL:ENSMUSG00000021635
ENSEMBL:ENSMUSG00000021635.15
KEGG Gene (Mus musculus):19356
Monarch:19356
NCBI Gene:19356
UCSC:Q6NXW6
Reference Transcript
RefSeq:NM_011233.3
RefSeq:NM_001283011.1
RefSeq:NM_001044371.2
Other Identifiers
103840_at
10411690
1448762_at
17295697
19356
4368559
4393293
4415224
4432735
4474354
4520134
4522826
4529794
4578710
4579105
4642529
4674896
4718518
4782727
4814074
5076268
5077298
5149381
5173319
5182740
5281364
5369234
5457757
5517693
5522538
5539782
5604739
A_51_P464630
A_51_P464633
GE35982
GO:0000077
GO:0000166
GO:0000278
GO:0000781
GO:0003682
GO:0003689
GO:0003824
GO:0005524
GO:0005634
GO:0005654
GO:0005694
GO:0005730
GO:0006260
GO:0006281
GO:0006974
GO:0007049
GO:0008156
GO:0016787
GO:0016887
GO:0023052
GO:0031389
GO:0031573
GO:0033314
GO:0042325
GO:0043226
GO:0140097
GO:0140657
ILMN_1222143
ILMN_3104289
mMC011590
Participates
as a component of
RAD17:RFC [nucleoplasm] (Mus musculus)
Inferred From
RAD17 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_035363.2
,
NP_001269940.1
,
NP_001037836.1
Ensembl
ENSMUST00000177848
,
ENSMUSP00000136292
,
ENSMUSP00000022136
,
ENSMUSG00000021635
,
ENSMUST00000022136
PRO
Q6NXW6
MGI
1333807
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