Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
Rptor [cytosol]
Stable Identifier
R-MMU-3006727
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
RPTOR, Q8K4Q0
Locations in the PathwayBrowser
Expand all
Autophagy (Mus musculus)
Macroautophagy (Mus musculus)
Active MTORC1 binds the ULK1 complex (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
Active MTORC1 phosphorylates ULK1 (Mus musculus)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
Rheb in the MTORC1 complex hydrolyses GTP (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Mus musculus)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular response to starvation (Mus musculus)
Amino acids regulate mTORC1 (Mus musculus)
RRAGA,B hydrolyzes GTP (Mus musculus)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Mus musculus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
mTORC1 binds RHEB:GTP (Mus musculus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Mus musculus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional Regulation by TP53 (Mus musculus)
TP53 Regulates Metabolic Genes (Mus musculus)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Intracellular signaling by second messengers (Mus musculus)
PIP3 activates AKT signaling (Mus musculus)
PTEN Regulation (Mus musculus)
Regulation of PTEN gene transcription (Mus musculus)
MAF1 translocates to the nucleus (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
mTORC1 phosphorylates MAF1 (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
MTOR signalling (Mus musculus)
AKT1S1 (PRAS40) binds mTORC1 (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Mus musculus)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
Energy dependent regulation of mTOR by LKB1-AMPK (Mus musculus)
AMPK phosphorylates Raptor in the mTORC1 complex (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
Formation of active mTORC1 complex (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Mus musculus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Mus musculus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
mTORC1 phosphorylates AKT1S1 (Mus musculus)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Mus musculus)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Mus musculus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
mTORC1-mediated signalling (Mus musculus)
Phosphorylation of 4E-BP1 by activated mTORC1 (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Mus musculus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Mus musculus)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Mus musculus)
Active mTORC1 complex [lysosomal membrane] (Mus musculus)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Mus musculus)
mTORC1 [cytosol] (Mus musculus)
Rptor [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q8K4Q0
Gene Names
Rptor
Reference Genes
ENSEMBL:ENSMUSG00000025583
UCSC:Q8K4Q0 Rptor
Participates
as a component of
mTORC1 [cytosol] (Mus musculus)
Other forms of this molecule
Rptor [nucleoplasm]
phospho-Rptor [cytosol]
Inferred From
RPTOR [cytosol]
(Homo sapiens)
Cross References
PRO
Q8K4Q0
MGI
1921620
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
