Reactome | KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer [plasma membrane]

KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer [plasma membrane]

Stable Identifier

R-MMU-265734

Type

Complex

Species

Mus musculus

Compartment

plasma membrane

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

x 4 ABCC8:Mg2+:ADP [plasma membrane] (Mus musculus)
x 4 Kcnj11 [plasma membrane] (Mus musculus)

Participates

as an input of

Meglitinides bind ABCC8 (Mus musculus)
SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) (Mus musculus)
KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Mus musculus)

as a component of

ABCC8:Meglitinides [plasma membrane] (Mus musculus)
ABCC8:SU drugs [plasma membrane] (Mus musculus)

Inferred From

KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer [plasma membrane] (Homo sapiens)

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