Reactome | phospho-Irs4 [plasma membrane]

phospho-Irs4 [plasma membrane]

Stable Identifier

R-MMU-2424302

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

p-Y-IRS4, Q9Z0Y7

Locations in the PathwayBrowser

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Signal Transduction (Mus musculus)

- Signaling by Receptor Tyrosine Kinases (Mus musculus)
  - Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Mus musculus)
    - IGF1R signaling cascade (Mus musculus)
      - IRS-related events triggered by IGF1R (Mus musculus)
        
        IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Mus musculus)
        
        IGF1,2:p-IGF1R:p-IRS1,2,4 [plasma membrane] (Mus musculus)
        
        p-IRS1,2,4 [plasma membrane] (Mus musculus)
        
        phospho-Irs4 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9Z0Y7

Gene Names

Irs4

Reference Genes

BioGPS Gene:16370 Irs4

ENSEMBL:ENSMUSG00000054667

ENSEMBL:ENSMUSG00000054667.8 Irs4

KEGG Gene (Mus musculus):16370 Irs4

Monarch:16370 Irs4

NCBI Gene:16370 Irs4

UCSC:Q9Z0Y7 Irs4

Reference Transcript

RefSeq:NM_010572.2 Irs4

Other Identifiers

10607059

1422248_at

1441429_at

16370

17545017

4640465

4667772

A_51_P344552

A_52_P57205

A_55_P2758789

GE118984

GO:0005158

GO:0005515

GO:0005829

GO:0005886

GO:0007165

GO:0008286

GO:0016020

GO:0023052

GO:0043548

ILMN_1226049

ILMN_2659295

mMC019246

mMR026738

Participates

as a member of

p-IRS1,2,4 [plasma membrane] (Mus musculus)

Other forms of this molecule

Irs4 [plasma membrane]

Inferred From

p-Y-IRS4 [plasma membrane] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at unknown position

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_034702.2

Ensembl

ENSMUSG00000054667, ENSMUST00000067841, ENSMUSP00000067085

PRO

Q9Z0Y7

MGI

1338009

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