Reactome | PHLPP2 [cytosol]

PHLPP2 [cytosol]

Stable Identifier

R-MMU-2327837

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

Q8BXA7

Locations in the PathwayBrowser

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Signal Transduction (Mus musculus)

- Intracellular signaling by second messengers (Mus musculus)
  - PIP3 activates AKT signaling (Mus musculus)
    - Negative regulation of the PI3K/AKT network (Mus musculus)
      - PHLPP dephosphorylates S473 in AKT (Mus musculus)
        
        PHLPP (Mn2+ cofactor) [cytosol] (Mus musculus)
        
        PHLPP [cytosol] (Mus musculus)
        
        PHLPP2 [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q8BXA7

Reference Genes

BioGPS Gene:244650

ENSEMBL:ENSMUSG00000031732

ENSEMBL:ENSMUSG00000031732.13

KEGG Gene (Mus musculus):244650

Monarch:244650

NCBI Gene:244650

Reference Transcript

RefSeq:NM_001122594.2

Other Identifiers

10575328

108814_at

1435601_at

1444593_at

17505455

244650

4335716

4343020

4460238

4462780

4553098

4567372

4622180

4670285

4674169

4699891

4718916

4764620

4850977

5047798

5079999

5088410

5125564

5155631

5280487

5450889

5518115

5526658

5593599

5606085

A_51_P105800

A_51_P389714

A_55_P2084068

GE124038

GE1441448

GO:0001917

GO:0003824

GO:0004721

GO:0004722

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005856

GO:0005886

GO:0005929

GO:0007165

GO:0016020

GO:0016787

GO:0017018

GO:0023052

GO:0042622

GO:0043226

GO:0043231

GO:0045171

GO:0046872

GO:0072686

GO:0140096

ILMN_2621095

mMC008488

Participates

as a member of

PHLPP [cytosol] (Mus musculus)

Inferred From

PHLPP2 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001116066.2

Ensembl

ENSMUST00000034175, ENSMUSG00000031732, ENSMUSP00000034175

PRO

Q8BXA7

MGI

2444928

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