RalA releases GDP and binds GTP (inferred from the simian RalA in Frech et al. 1990). The reaction is enhanced by guanine nucleotide exchange factors (GEFs) and opposed by GTPase-activating proteins (GAPs) which activate the intrinsic GTPase activity of RalA (Chen et al. 2011).
Cheng, A, Yu, G, Decker, S, Xiong, T, Chen, XW, Saltiel, AR, Leto, D
Wittinghofer, A, Chardin, P, Schlichting, I, Frech, M
© 2023 Reactome