Platelet glycoprotein 4 binds ligands

Stable Identifier
R-MMU-2187263
Type
Reaction [binding]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Platelet glycoprotein 4 binds ligands

Cd36 (Platelet glycoprotein IV) binds oxidized LDL, beta-glucan, lipoteichoic acid, oxidized phospholipids, phosphatidylserine, and phosphatidylinositol.

Literature References
PubMed ID Title Journal Year
15722561 Phosphocholine as a pattern recognition ligand for CD36

Boullier, A, Almazan, F, Dennis, EA, Witztum, JL, Hartvigsen, K, Green, SR, Steinberg, D, Quehenberger, O, Friedman, P, Harkewicz, R

J Lipid Res 2005
7685021 CD36 is a receptor for oxidized low density lipoprotein

Bryant, CM, White, RT, Madden, KS, Protter, AA, Stanton, LW, Endemann, G

J Biol Chem 1993
10734051 The binding of oxidized low density lipoprotein to mouse CD36 is mediated in part by oxidized phospholipids that are associated with both the lipid and protein moieties of the lipoprotein

Boullier, A, Dennis, EA, Witztum, JL, Green, SR, Hörkkö, S, Gillotte, KL, Steinberg, D, Quehenberger, O, Friedman, P

J Biol Chem 2000
10772654 Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species

Cohen, PA, Schmitt, D, Febbraio, M, Frazier, WA, Sheibani, N, Hajjar, DP, Silverstein, RL, Hoff, HF, Podrez, EA, Hazen, SL

J Clin Invest 2000
10339590 Receptors for oxidized low-density lipoprotein on elicited mouse peritoneal macrophages can recognize both the modified lipid moieties and the modified protein moieties: implications with respect to macrophage recognition of apoptotic cells

Dennis, EA, Witztum, JL, Hörkkö, S, Gillotte, KL, Steinberg, D, Bird, DA, Friedman, P

Proc Natl Acad Sci U S A 1999
17101731 Oxidized phosphatidylserine-CD36 interactions play an essential role in macrophage-dependent phagocytosis of apoptotic cells

Silverstein, R, Febbraio, M, Greenberg, ME, Hazen, SL, Sun, M, Zhang, R

J Exp Med 2006
15690042 CD36 is a sensor of diacylglycerides

Beutler, B, Sovath, S, Du, X, Hartung, T, Georgel, P, Rutschmann, S, Crozat, K, Hoebe, K, Shamel, L, Mudd, S, Zähringer, U

Nature 2005
12376530 Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages

Silverstein, R, Freeman, MW, Moore, KJ, Febbraio, M, Hoff, HF, Andersson, L, Podrez, EA, Kunjathoor, VV, Rhee, JS, Koehn, S

J Biol Chem 2002
12150950 Adipocytes recognize and degrade oxidized low density lipoprotein through CD36

Kuniyasu, A, Nakayama, H, Hayashi, S

Biochem Biophys Res Commun 2002
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