Marco binds ligands

Stable Identifier
Reaction [binding]
Mus musculus
SVG |   | PPTX  | SBGN
Marco binds ligands

Marco binds lipopolysaccharide and lipoteichoic acid.

Literature References
PubMed ID Title Journal Year
16984918 MARCO mediates silica uptake and toxicity in alveolar macrophages from C57BL/6 mice

Holian, A, Mayfair, JK, Thakur, SA, Hamilton, RF

J. Biol. Chem. 2006
10224290 Role of the scavenger receptor MARCO in alveolar macrophage binding of unopsonized environmental particles

Kobzik, L, Kodama, T, Palecanda, A, Tryggvason, K, Imrich, A, Al-Mutairi, E, Koziel, H, Suzuki, H, Qin, G, Paulauskis, J

J. Exp. Med. 1999
9232452 Macrophage scavenger receptor MARCO: in vitro and in vivo regulation and involvement in the anti-bacterial host defense

Kraal, G, Döpp, EA, Tryggvason, K, Elomaa, O, Broug-Holub, E, Kangas, M, van der Laan, LJ

Immunol Lett 1997
16524885 A phage display screen and binding studies with acetylated low density lipoprotein provide evidence for the importance of the scavenger receptor cysteine-rich (SRCR) domain in the ligand-binding function of MARCO

Pikkarainen, T, Tuuttila, A, Chen, Y, Sun, Y, Tryggvason, K, Ojala, JR, Sankala, M, Isenman, DE

J Biol Chem 2006
20810988 The class A scavenger receptor, macrophage receptor with collagenous structure, is the major phagocytic receptor for Clostridium sordellii expressed by human decidual macrophages

Medeiros, AI, Aronoff, DM, Kobzik, L, Serezani, CH, Harris, LH, Curtis, JL, Hao, Y, Thelen, T

J Immunol 2010
17332894 Protection against inhaled oxidants through scavenging of oxidized lipids by macrophage receptors MARCO and SR-AI/II

Kobzik, L, Kleeberger, SR, Soininen, R, Arredouani, M, Dahl, M, Bauer, AK, Tryggvason, K

J. Clin. Invest. 2007
12097327 Characterization of recombinant soluble macrophage scavenger receptor MARCO

Pikkarainen, T, Brännström, A, Engel, J, Schulthess, T, Morgunova, E, Bergmann, U, Tryggvason, K, Sankala, M

J Biol Chem 2002
16882874 Role of scavenger receptor MARCO in macrophage responses to CpG oligodeoxynucleotides

Kobzik, L, Sulahian, TH, Arredouani, M, Józefowski, S

J. Leukoc. Biol. 2006
23197261 MARCO is required for TLR2- and Nod2-mediated responses to Streptococcus pneumoniae and clearance of pneumococcal colonization in the murine nasopharynx

Weiser, JN, Roche, AM, Mossman, KL, Chauvin, SE, Dorrington, MG, Bowdish, DM, Tu, Z

J. Immunol. 2013
7867067 Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed in a subset of macrophages

Kraal, G, Thesleff, I, Sormunen, R, Liakka, A, Tuukkanen, J, Sahlberg, C, Tryggvason, K, Elomaa, O, Kangas, M

Cell 1995
16525990 MARCO, an innate activation marker of macrophages, is a class A scavenger receptor for Neisseria meningitidis

Gordon, S, Kraal, G, Chen, Y, Pikkarainen, T, Peiser, L, Sankala, M, Tryggvason, K, Mukhopadhyay, S

Eur. J. Immunol. 2006
20375573 SR-A, MARCO and TLRs differentially recognise selected surface proteins from Neisseria meningitidis: an example of fine specificity in microbial ligand recognition by innate immune receptors

Plüddemann, A, Mukhopadhyay, S, Gordon, S, Pizza, M, Tryggvason, K, Rappuoli, R, Sankala, M, Savino, S

J Innate Immun 2009
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