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EGF-like ligand:p-6Y-EGFR:p-Y472,771,783,1254-PLCG1 [plasma membrane]
Stable Identifier
R-MMU-212703
Type
Complex
Species
Mus musculus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by EGFR (Mus musculus)
EGFR interacts with phospholipase C-gamma (Mus musculus)
Active PLC-gamma1 dissociates from EGFR (Mus musculus)
EGF-like ligand:p-6Y-EGFR:p-Y472,771,783,1254-PLCG1 [plasma membrane] (Mus musculus)
EGFR activates PLC-gamma1 by phosphorylation (Mus musculus)
EGF-like ligand:p-6Y-EGFR:p-Y472,771,783,1254-PLCG1 [plasma membrane] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
EGF-like ligands:p-6Y EGFR dimer [plasma membrane]
(Mus musculus)
phospho-p-4Y-PLCG1 [plasma membrane]
(Mus musculus)
Participates
as an input of
Active PLC-gamma1 dissociates from EGFR (Mus musculus)
as an output of
EGFR activates PLC-gamma1 by phosphorylation (Mus musculus)
Inferred From
EGF-like ligand:p-6Y-EGFR:p-Y472,771,783,1254-PLCG1 [plasma membrane]
(Homo sapiens)
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