Murine MKK4 kinase is phosphorylated and activated by Phospho TAK1:Phospho TAB1:Phospho TAB2 kinase complex

Stable Identifier
R-MMU-209329
Type
Reaction [transition]
Species
Mus musculus
Compartment
General
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Murine MKK4 kinase is phosphorylated and activated by Phospho TAK1:Phospho TAB1:Phospho TAB2 kinase complex

In Mouse, MKK4 kinase is phosphorylated in its activation loop at Ser255 and Thr259 by phosphorylated TAK1 kinase.

Literature References
PubMed ID Title Journal Year
15218018 Activation mechanism of c-Jun amino-terminal kinase in the course of neural differentiation of P19 embryonic carcinoma cells

Akiyama, S, Yonezawa, T, Kudo, TA, Li, MG, Wang, H, Ito, M, Yoshioka, K, Ninomiya-Tsuji, J, Matsumoto, K, Kanamaru, R, Tamura, S, Kobayashi, T

J Biol Chem 2004
Participants
Catalyst Activity

protein serine/threonine kinase activity of Phospho TAK1 [cytosol]

Orthologous Events
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