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PFN [cytosol]
Stable Identifier
R-MMU-203077
Type
Set [CandidateSet]
Species
Mus musculus
Compartment
cytosol
Synonyms
Profilin, (PFN1,PFN2)
Locations in the PathwayBrowser
Expand all
Developmental Biology (Mus musculus)
Nervous system development (Mus musculus)
Axon guidance (Mus musculus)
Signaling by ROBO receptors (Mus musculus)
Recruitment of Profilin by Ena/VASP proteins (Mus musculus)
PFN [cytosol] (Mus musculus)
SLIT2:ROBO1:Ena/VASP:PFN [plasma membrane] (Mus musculus)
PFN [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase Effectors (Mus musculus)
RHO GTPases Activate Formins (Mus musculus)
Activated FMNL3 binds G-actin (Mus musculus)
Profilin:G-actin [cytosol] (Mus musculus)
PFN [cytosol] (Mus musculus)
RHOC:GTP:FMNL3:G-actin [plasma membrane] (Mus musculus)
Profilin:G-actin [cytosol] (Mus musculus)
PFN [cytosol] (Mus musculus)
Association of profilin with monomeric actin (Mus musculus)
PFN [cytosol] (Mus musculus)
Profilin:G-actin [cytosol] (Mus musculus)
PFN [cytosol] (Mus musculus)
CDC42:GTP:FMNL2 binds Profilin:G-actin (Mus musculus)
CDC42:FMNL2:Profilin:G-actin [plasma membrane] (Mus musculus)
Profilin:G-actin [cytosol] (Mus musculus)
PFN [cytosol] (Mus musculus)
Profilin:G-actin [cytosol] (Mus musculus)
PFN [cytosol] (Mus musculus)
Profilin:G-actin binds MKL1 (Mus musculus)
Profilin:G-actin [cytosol] (Mus musculus)
PFN [cytosol] (Mus musculus)
Profilin:G-actin:MKL1 [cytosol] (Mus musculus)
Profilin:G-actin [cytosol] (Mus musculus)
PFN [cytosol] (Mus musculus)
RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 (Mus musculus)
Profilin:G-actin:MKL1 [cytosol] (Mus musculus)
Profilin:G-actin [cytosol] (Mus musculus)
PFN [cytosol] (Mus musculus)
RHOA:GTP:DIAPH1:EVL:Profilin:G-actin [plasma membrane] (Mus musculus)
Profilin:G-actin [cytosol] (Mus musculus)
PFN [cytosol] (Mus musculus)
SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin (Mus musculus)
RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Mus musculus)
Profilin:G-actin [cytosol] (Mus musculus)
PFN [cytosol] (Mus musculus)
SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Mus musculus)
RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Mus musculus)
Profilin:G-actin [cytosol] (Mus musculus)
PFN [cytosol] (Mus musculus)
SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Mus musculus)
Profilin:G-actin [cytosol] (Mus musculus)
PFN [cytosol] (Mus musculus)
SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Mus musculus)
RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Mus musculus)
Profilin:G-actin [cytosol] (Mus musculus)
PFN [cytosol] (Mus musculus)
Participants
candidates
Pfn1 [cytosol] (Mus musculus)
Pfn2 [cytosol] (Mus musculus)
Participant Of
input
Association of profilin with monomeric actin
Recruitment of Profilin by Ena/VASP proteins
hasComponent
Profilin:G-actin [cytosol]
SLIT2:ROBO1:Ena/VASP:PFN [plasma membrane]
Inferred From
PFN [cytosol] (Homo sapiens)
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