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About
What is Reactome ?
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Team
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Table of Contents
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UBE2N:UBE2V1 [cytosol]
Stable Identifier
R-MMU-202463
Type
Complex
Species
Mus musculus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Autophagy (Mus musculus)
Macroautophagy (Mus musculus)
Selective autophagy (Mus musculus)
Aggrephagy (Mus musculus)
Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Mus musculus)
Misfolded proteins:PRKN:UBE2N:UBE2V1:Ub [cytosol] (Mus musculus)
Ub:UBE2N:UBE2V1:PRKN [cytosol] (Mus musculus)
Ub:UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Ub:UBE2N:UBE2V1:PRKN [cytosol] (Mus musculus)
Ub:UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Parkin binds Ub:UBE2N:UBE2V1 (Mus musculus)
Ub:UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Ub:UBE2N:UBE2V1:PRKN [cytosol] (Mus musculus)
Ub:UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Parkin transfers Ub to misfolded proteins (Mus musculus)
Misfolded proteins:PRKN:UBE2N:UBE2V1:Ub [cytosol] (Mus musculus)
Ub:UBE2N:UBE2V1:PRKN [cytosol] (Mus musculus)
Ub:UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Ub:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1:PRKN [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 (Mus musculus)
PolyUb:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1:PRKN [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1:PRKN [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Mus musculus)
PolyUb:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1:PRKN [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Ub:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1:PRKN [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Mitophagy (Mus musculus)
PINK1-PRKN Mediated Mitophagy (Mus musculus)
PRKN ubiquitinates MOM substrates (Mus musculus)
UBE2D2,UBE2D3,UBE2N:UBE2V1,UBE2L3 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
TCR signaling (Mus musculus)
Downstream TCR signaling (Mus musculus)
Auto-ubiquitination of TRAF6 (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Ubiquitination of NEMO by TRAF6 (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Cytokine Signaling in Immune system (Mus musculus)
Signaling by Interleukins (Mus musculus)
Interleukin-1 family signaling (Mus musculus)
Interleukin-1 signaling (Mus musculus)
K63polyUb-IRAK1 dissociates (Mus musculus)
K63polyUb-hp-IRAK1:p-Pellino-1,2,(3):UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Pellino ubiquitinates IRAK1 (Mus musculus)
K63polyUb-hp-IRAK1:p-Pellino-1,2,(3):UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
TAK1 is activated within the TAK1 complex (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
TRAF6 is K63 poly-ubiquitinated (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 dissociates from hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Interleukin-17 signaling (Mus musculus)
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Innate Immune System (Mus musculus)
C-type lectin receptors (CLRs) (Mus musculus)
CLEC7A (Dectin-1) signaling (Mus musculus)
K63polyUb-TRAF6 ubiquitinates TAK1 (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
TRAF6 oligomer autoubiquitinates (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Ubiquitination of NEMO by TRAF6 (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Fc epsilon receptor (FCERI) signaling (Mus musculus)
FCERI mediated NF-kB activation (Mus musculus)
Auto-ubiquitination of TRAF6 (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Ubiquitination of NEMO by TRAF6 (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Mus musculus)
NOD1/2 Signaling Pathway (Mus musculus)
RIP2 induces K63-linked ubiquitination of NEMO (Mus musculus)
TRAF6 E3/E2 ubiquitin ligase complex [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
RIP2 is K63 polyubiquitinated (Mus musculus)
RIP2 ubiquitin ligases [cytosol] (Mus musculus)
TRAF6 E3/E2 ubiquitin ligase complex [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Toll-like Receptor Cascades (Mus musculus)
Toll Like Receptor 10 (TLR10) Cascade (Mus musculus)
MyD88 cascade initiated on plasma membrane (Mus musculus)
IRAK1 recruits IKK complex (Mus musculus)
Pellino ubiquitinates hp-IRAK1 (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Toll Like Receptor 2 (TLR2) Cascade (Mus musculus)
Toll Like Receptor TLR1:TLR2 Cascade (Mus musculus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
IRAK1 recruits IKK complex (Mus musculus)
Pellino ubiquitinates hp-IRAK1 (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Toll Like Receptor TLR6:TLR2 Cascade (Mus musculus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
IRAK1 recruits IKK complex (Mus musculus)
Pellino ubiquitinates hp-IRAK1 (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Toll Like Receptor 3 (TLR3) Cascade (Mus musculus)
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Toll Like Receptor 4 (TLR4) Cascade (Mus musculus)
MyD88-independent TLR4 cascade (Mus musculus)
TRIF (TICAM1)-mediated TLR4 signaling (Mus musculus)
IKK complex recruitment mediated by RIP1 (Mus musculus)
K63-linked ubiquitination of RIP1 bound to the activated TLR complex (Mus musculus)
RIP1 ubiqutin ligases [cytosol] (Mus musculus)
TRAF6 E3/E2 ubiquitin ligase complex [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
IRAK1 recruits IKK complex (Mus musculus)
Pellino ubiquitinates hp-IRAK1 (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Toll Like Receptor 5 (TLR5) Cascade (Mus musculus)
MyD88 cascade initiated on plasma membrane (Mus musculus)
IRAK1 recruits IKK complex (Mus musculus)
Pellino ubiquitinates hp-IRAK1 (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Mus musculus)
MyD88 dependent cascade initiated on endosome (Mus musculus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Mus musculus)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Mus musculus)
Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
(Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
Toll Like Receptor 9 (TLR9) Cascade (Mus musculus)
MyD88 dependent cascade initiated on endosome (Mus musculus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Mus musculus)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Mus musculus)
Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
(Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
Activated TAK complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Mus musculus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1 [cytosol] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Ube2n [cytosol]
(Mus musculus)
Ube2v1 [cytosol]
(Mus musculus)
Participates
as an output of
Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
(Mus musculus)
UBE2N:UBE2V1 dissociates from hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 (Mus musculus)
K63polyUb-IRAK1 dissociates (Mus musculus)
Ubiquitination of NEMO by TRAF6 (Mus musculus)
K63polyUb-TRAF6 ubiquitinates TAK1 (Mus musculus)
TRAF6 oligomer autoubiquitinates (Mus musculus)
Auto-ubiquitination of TRAF6 (Mus musculus)
Auto-ubiquitination of TRAF6 (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
Pellino ubiquitinates hp-IRAK1 (Mus musculus)
as an input of
Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
(Mus musculus)
Ubiquitination of NEMO by TRAF6 (Mus musculus)
K63polyUb-TRAF6 ubiquitinates TAK1 (Mus musculus)
TRAF6 oligomer autoubiquitinates (Mus musculus)
Auto-ubiquitination of TRAF6 (Mus musculus)
Auto-ubiquitination of TRAF6 (Mus musculus)
Ubiquitination of IKBKG by TRAF6 (Mus musculus)
Pellino ubiquitinates hp-IRAK1 (Mus musculus)
as a component of
K63polyUb-hp-IRAK1:p-Pellino-1,2,(3):UBE2N:UBE2V1 [cytosol] (Mus musculus)
TRAF6 E3/E2 ubiquitin ligase complex [cytosol] (Mus musculus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Mus musculus)
Ub:UBE2N:UBE2V1 [cytosol] (Mus musculus)
UBE2N:UBE2V1:PRKN [cytosol] (Mus musculus)
as a member of
UBE2D2,UBE2D3,UBE2N:UBE2V1,UBE2L3 [cytosol] (Mus musculus)
Inferred From
UBE2N:UBE2V1 [cytosol]
(Homo sapiens)
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