Reactome | Epithelial-cadherin precursor [plasma membrane]

Epithelial-cadherin precursor [plasma membrane]

Stable Identifier

R-MMU-199081

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

CADH1_MOUSE, Cdh1

External Reference Information

External Reference

UniProt:P09803 Cdh1

Gene Names

Cdh1

Chain

signal peptide:1-23, propeptide:24-156, chain:157-884, chain:703-884, chain:734-884, chain:753-884

Reference Genes

BioGPS Gene:12550 Cdh1

dbSNP Gene:12550 Cdh1

KEGG Gene (Mus musculus):12550 Cdh1

Monarch:12550 Cdh1

NCBI Gene:12550 Cdh1

UCSC:P09803 Cdh1

Reference Transcript

RefSeq:NM_009864.3 Cdh1

Participant Of

input

Epithelial cadherin binds to KLRG1 in mice

hasComponent

E-cadherin bound to KLRG1 [plasma membrane]

Cross References

RefSeq

NP_033994.1

DOCK Blaster

3Q2N, 2OMW, 1Q1P, 2QVF, 3QRB, 3IFQ, 1I7X, 3LNF, 3Q2V, 3LNE, 3LNH, 4QD2, 1I7W, 3LNG, 1EDH, 3LNI, 1FF5, 3Q2L

PRO

P09803

PDB

1I7W, 1FF5, 4QD2, 1I7X, 3LNG, 2QVF, 3QRB, 3LNH, 3Q2N, 1SUH, 3Q2L, 1EDH, 3IFQ, 1Q1P, 2OMW, 3Q2V, 3LNE, 3LNI, 3LNF

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P09803 Cdh1	1	Epithelial-cadherin precursor [plasma membrane] (R-MMU-199081)	0.871	12
UniProt:Q02248 Ctnnb1	12	phospho-p-S552-CTNNB1 [cytosol] (R-MMU-3134933) phospho-p-S552-CTNNB1 [nucleoplasm] (R-MMU-3134926) CTNNB1(116-376) [cytosol] (R-MMU-202950) CTNNB1(1-115) [cytosol] (R-MMU-202930) CTNNB1 [plasma membrane] (R-MMU-9038440) phospho-p-S45 CTNNB1 [cytosol] (R-MMU-8942363) phospho-p-T41,S45 CTNNB1 [cytosol] (R-MMU-8942367) phospho-p-S37,T41,S45, CTNNB1 [cytosol] (R-MMU-8942369) beta-catenin [cytosol] (R-MMU-206225) phospho-p-S33,S37,T41,S45 CTNNB1 [cytosol] (R-MMU-8942374) CTNNB1 [nucleoplasm] (R-MMU-3451168) CTNNB1 [cytosol] (R-MMU-448839)	0.811	15
UniProt:O60716-29 CTNND1			0.618	3
UniProt:A5HZZ4 A5HZZ4			0.576	6
UniProt:P35222 CTNNB1	24	CTNNB1 S45P [cytosol] (R-HSA-4791272) CTNNB1 S45F [cytosol] (R-HSA-4791268) pT41,S45-CTNNB1 S37F [cytosol] (R-HSA-4839621) pT41,S45-CTNNB1 S37A [cytosol] (R-HSA-4839619) pT41,S45-CTNNB1 S37C [cytosol] (R-HSA-4839617) pS37,T41,S45-CTNNB1 S33C [cytosol] (R-HSA-4839630) pS37,T41,S45-CTNNB1 S33F [cytosol] (R-HSA-4839628) pS37,T41,S45-CTNNB1 S33P [cytosol] (R-HSA-4839626) pS37,T41,S45-CTNNB1 S33Y [cytosol] (R-HSA-4839625) pS45-CTNNB1 T41A [cytosol] (R-HSA-4836868) pS45-CTNNB1 T41I [cytosol] (R-HSA-4839612) Ub-K,p-Y-CTNNB1 [cytosol] (R-HSA-8877006) p-Y-CTNNB1 [cytosol] (R-HSA-8876940) p-S552-CTNNB1 [nucleoplasm] (R-HSA-3134926) p-S552-CTNNB1 [cytosol] (R-HSA-3134933) CTNNB1(116-376) [cytosol] (R-HSA-202950) CTNNB1(1-115) [cytosol] (R-HSA-202930) CTNNB1 [plasma membrane] (R-HSA-9038440) p-S45 CTNNB1 [cytosol] (R-HSA-8942363) p-T41,S45 CTNNB1 [cytosol] (R-HSA-8942367) p-S37,T41,S45, CTNNB1 [cytosol] (R-HSA-8942369) p-S33,S37,T41,S45 CTNNB1 [cytosol] (R-HSA-8942374) CTNNB1 [cytosol] (R-HSA-448839) CTNNB1 [nucleoplasm] (R-HSA-3451168)	0.527	3
UniProt:Q13309 SKP2	2	SKP2 [cytosol] (R-HSA-975495) SKP2 [nucleoplasm] (R-HSA-975554)	0.524	2