Reactome | Epithelial-cadherin precursor [plasma membrane]

Epithelial-cadherin precursor [plasma membrane]

Stable Identifier

R-MMU-199081

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

CADH1_MOUSE, Cdh1

External Reference Information

External Reference

UniProt:P09803 Cdh1

Gene Names

Cdh1

Chain

signal peptide:1-23, propeptide:24-156, chain:157-884, chain:703-884, chain:734-884, chain:753-884

Reference Genes

BioGPS Gene:12550 Cdh1

KEGG Gene (Mus musculus):12550 Cdh1

Monarch:12550 Cdh1

NCBI Gene:12550 Cdh1

UCSC:P09803 Cdh1

Reference Transcript

RefSeq:NM_009864.3 Cdh1

Participates

as a component of

E-cadherin bound to KLRG1 [plasma membrane] (Mus musculus)

as an input of

Epithelial cadherin binds to KLRG1 in mice (Mus musculus)

Other forms of this molecule

CDH1(155-700) [plasma membrane]

CDH1(701-882) [extracellular region]

CDH1(155-750) [plasma membrane]

CDH1(751-882) [plasma membrane]

CDH1(155-882) [plasma membrane]

Cross References

RefSeq

NP_033994.1

PRO

P09803

MGI

88354

PDB

7AR4, 3LNI, 3LNH, 1I7W, 1FF5, 3Q2V, 3LNE, 3LNF, 2OMW, 3Q2L, 1I7X, 4QD2, 2QVF, 1SUH, 3IFQ, 3LNG, 1EDH, 1Q1P, 3Q2N, 3QRB

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P09803 Cdh1	6	Epithelial-cadherin precursor [plasma membrane] (R-MMU-199081) CDH1(155-700) [plasma membrane] (R-MMU-2534244) CDH1(701-882) [extracellular region] (R-MMU-2534158) CDH1(155-750) [plasma membrane] (R-MMU-202940) CDH1(751-882) [plasma membrane] (R-MMU-202929) CDH1(155-882) [plasma membrane] (R-MMU-198003)	0.871	12
UniProt:Q02248 Ctnnb1	13	Ctnnb1 [nucleoplasm] (R-MMU-9735212) phospho-Ctnnb1 [nucleoplasm] (R-MMU-3134926) phospho-Ctnnb1 [cytosol] (R-MMU-3134933) Ctnnb1 [nucleoplasm] (R-MMU-3451168) Ctnnb1 [cytosol] (R-MMU-448839) Ctnnb1 [cytosol] (R-MMU-202930) Ctnnb1 [cytosol] (R-MMU-202950) phospho-Ctnnb1 [cytosol] (R-MMU-8942374) beta-catenin [cytosol] (R-MMU-206225) phospho-Ctnnb1 [cytosol] (R-MMU-8942369) phospho-Ctnnb1 [cytosol] (R-MMU-8942367) phospho-Ctnnb1 [cytosol] (R-MMU-8942363) Ctnnb1 [plasma membrane] (R-MMU-9038440)	0.858	16
UniProt:O60716-29 CTNND1			0.618	3
UniProt:A5HZZ4 A5HZZ4			0.576	6
UniProt:P28828 PTPRM			0.576	3
UniProt:P35222 CTNNB1	20	CTNNB1 S45A [cytosol] (R-HSA-9663982) CTNNB1 S45F [cytosol] (R-HSA-4791268) CTNNB1 S45C [cytosol] (R-HSA-9663983) CTNNB1 S45Y [cytosol] (R-HSA-9663975) CTNNB1 S45N [cytosol] (R-HSA-9663984) CTNNB1 S45P [cytosol] (R-HSA-4791272) pT41,S45-CTNNB1 S37P [cytosol] (R-HSA-9663981) pT41,S45-CTNNB1 S37F [cytosol] (R-HSA-4839621) pT41,S45-CTNNB1 S37A [cytosol] (R-HSA-4839619) pT41,S45-CTNNB1 S37Y [cytosol] (R-HSA-9663978) pT41,S45-CTNNB1 S37C [cytosol] (R-HSA-4839617) pS37,T41,S45-CTNNB1 S33A [cytosol] (R-HSA-9663976) pS37,T41,S45-CTNNB1 S33T [cytosol] (R-HSA-9663977) pS37,T41,S45-CTNNB1 S33C [cytosol] (R-HSA-4839630) pS37,T41,S45-CTNNB1 S33F [cytosol] (R-HSA-4839628) pS37,T41,S45-CTNNB1 S33P [cytosol] (R-HSA-4839626) pS37,T41,S45-CTNNB1 S33Y [cytosol] (R-HSA-4839625) pS45-CTNNB1 T41N [cytosol] (R-HSA-9663980) pS45-CTNNB1 T41A [cytosol] (R-HSA-4836868) pS45-CTNNB1 T41I [cytosol] (R-HSA-4839612)	0.527	3
UniProt:Q62470	1	Itga3 [plasma membrane] (R-MMU-204441)	0.524	4
UniProt:Q13309 SKP2	3	SKP2 [nucleoplasm] (R-HSA-975554) PolyUb-SKP2 [nucleoplasm] (R-HSA-9687073) SKP2 [cytosol] (R-HSA-975495)	0.524	2

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