Reactome | Fcer1a [plasma membrane]

Fcer1a [plasma membrane]

Stable Identifier

R-MMU-197802

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

FCER1A, P20489

Locations in the PathwayBrowser

Expand all

Immune System (Mus musculus)

- Innate Immune System (Mus musculus)
  - Fc epsilon receptor (FCERI) signaling (Mus musculus)
    - Allergen dependent IgE bound FCERI aggregation (Mus musculus)
      - FCERI:IgE [plasma membrane] (Mus musculus)
        
        FCERI [plasma membrane] (Mus musculus)
        
        Fcer1a [plasma membrane] (Mus musculus)
      - FCERI:IgE:Allergen aggregate [plasma membrane] (Mus musculus)
        
        FCERI:IgE aggregate [plasma membrane] (Mus musculus)
        
        FCERI:IgE [plasma membrane] (Mus musculus)
        
        FCERI [plasma membrane] (Mus musculus)
        
        Fcer1a [plasma membrane] (Mus musculus)
    - FCERI mediated Ca+2 mobilization (Mus musculus)
      - Phosphorylation of TEC kinases by p-SYK (Mus musculus)
        
        Clustered p:LYN:p-FCERI:IgE:allergen:p-6Y-SYK [plasma membrane] (Mus musculus)
        
        Allergen:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Mus musculus)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Mus musculus)
        
        p-FCERI aggregate [plasma membrane] (Mus musculus)
        
        p-FCERI [plasma membrane] (Mus musculus)
        
        Fcer1a [plasma membrane] (Mus musculus)
    - FCERI mediated MAPK activation (Mus musculus)
      - Phosphorylation of SHC by SYK kinase (Mus musculus)
        
        Clustered p:LYN:p-FCERI:IgE:allergen:p-6Y-SYK [plasma membrane] (Mus musculus)
        
        Allergen:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Mus musculus)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Mus musculus)
        
        p-FCERI aggregate [plasma membrane] (Mus musculus)
        
        p-FCERI [plasma membrane] (Mus musculus)
        
        Fcer1a [plasma membrane] (Mus musculus)
      - Phosphorylation of SLP-76 by p-SYK (Mus musculus)
        
        Clustered p:LYN:p-FCERI:IgE:allergen:p-6Y-SYK [plasma membrane] (Mus musculus)
        
        Allergen:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Mus musculus)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Mus musculus)
        
        p-FCERI aggregate [plasma membrane] (Mus musculus)
        
        p-FCERI [plasma membrane] (Mus musculus)
        
        Fcer1a [plasma membrane] (Mus musculus)
    - FCERI mediated NF-kB activation (Mus musculus)
      - Phosphorylation of PKC-theta (Mus musculus)
        
        Allergen:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Mus musculus)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Mus musculus)
        
        p-FCERI aggregate [plasma membrane] (Mus musculus)
        
        p-FCERI [plasma membrane] (Mus musculus)
        
        Fcer1a [plasma membrane] (Mus musculus)
    - IgE binds FCERI (Mus musculus)
      - FCERI [plasma membrane] (Mus musculus)
        
        Fcer1a [plasma membrane] (Mus musculus)
      - FCERI:IgE [plasma membrane] (Mus musculus)
        
        FCERI [plasma membrane] (Mus musculus)
        
        Fcer1a [plasma membrane] (Mus musculus)
    - Phosphorylation of LAT by p-SYK (Mus musculus)
      - Clustered p:LYN:p-FCERI:IgE:allergen:p-6Y-SYK [plasma membrane] (Mus musculus)
        
        Allergen:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Mus musculus)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Mus musculus)
        
        p-FCERI aggregate [plasma membrane] (Mus musculus)
        
        p-FCERI [plasma membrane] (Mus musculus)
        
        Fcer1a [plasma membrane] (Mus musculus)
    - Phosphorylation of beta and gamma subunits by LYN (Mus musculus)
      - Allergen:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Mus musculus)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Mus musculus)
        
        p-FCERI aggregate [plasma membrane] (Mus musculus)
        
        p-FCERI [plasma membrane] (Mus musculus)
        
        Fcer1a [plasma membrane] (Mus musculus)
      - FCERI:IgE:Allergen aggregate [plasma membrane] (Mus musculus)
        
        FCERI:IgE aggregate [plasma membrane] (Mus musculus)
        
        FCERI:IgE [plasma membrane] (Mus musculus)
        
        FCERI [plasma membrane] (Mus musculus)
        
        Fcer1a [plasma membrane] (Mus musculus)
    - Recruitment of SYK to p-FCERI gamma subunit (Mus musculus)
      - Allergen:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Mus musculus)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Mus musculus)
        
        p-FCERI aggregate [plasma membrane] (Mus musculus)
        
        p-FCERI [plasma membrane] (Mus musculus)
        
        Fcer1a [plasma membrane] (Mus musculus)
      - Clustered p:LYN:p-FCERI:IgE:allergen:SYK [plasma membrane] (Mus musculus)
        
        Allergen:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Mus musculus)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Mus musculus)
        
        p-FCERI aggregate [plasma membrane] (Mus musculus)
        
        p-FCERI [plasma membrane] (Mus musculus)
        
        Fcer1a [plasma membrane] (Mus musculus)
    - Role of LAT2/NTAL/LAB on calcium mobilization (Mus musculus)
      - Phosphorylation of NTAL by p-SYK/Lyn (Mus musculus)
        
        Clustered p:LYN:p-FCERI:IgE:allergen:p-6Y-SYK [plasma membrane] (Mus musculus)
        
        Allergen:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Mus musculus)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Mus musculus)
        
        p-FCERI aggregate [plasma membrane] (Mus musculus)
        
        p-FCERI [plasma membrane] (Mus musculus)
        
        Fcer1a [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P20489

Gene Names

Fcer1a

Reference Genes

BioGPS Gene:14125 Fcer1a

ENSEMBL:ENSMUSG00000005339

ENSEMBL:ENSMUSG00000005339.11 Fcer1a

KEGG Gene (Mus musculus):14125 Fcer1a

Monarch:14125 Fcer1a

NCBI Gene:14125 Fcer1a

UCSC:P20489 Fcer1a

Reference Transcript

RefSeq:NM_010184.2 Fcer1a

Other Identifiers

101209_at

10360338

14125

1421775_at

17229974

4436679

4880754

4917781

5156392

5501614

5578950

A_55_P2120244

GE1471208

GO:0001812

GO:0001820

GO:0002376

GO:0004888

GO:0005515

GO:0005886

GO:0006954

GO:0007165

GO:0007166

GO:0009897

GO:0009986

GO:0016020

GO:0016068

GO:0016192

GO:0019370

GO:0019722

GO:0019767

GO:0019768

GO:0019863

GO:0023052

GO:0032725

GO:0032752

GO:0032765

GO:0036211

GO:0038095

GO:0042092

GO:0043303

GO:0043306

GO:0043308

GO:0045121

GO:0050731

GO:0050776

GO:0050850

GO:0051649

GO:0060089

ILMN_2771342

ILMN_2863390

J05018_s_at

mMC025241

Participates

as a component of

Inferred From

FCER1A [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_034314.2

Ensembl

ENSMUSG00000005339, ENSMUSP00000056882, ENSMUST00000049706

PRO

P20489

MGI

95494

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