Reactome | H2-Q10 [plasma membrane]

H2-Q10 [plasma membrane]

Stable Identifier

R-MMU-197572-10

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

HLA class I histocompatibility antigen, alpha chain F precursor, P01898

Locations in the PathwayBrowser

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Immune System (Mus musculus)

- Adaptive Immune System (Mus musculus)
  - Class I MHC mediated antigen processing & presentation (Mus musculus)
    - Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Mus musculus)
      - Expression of peptide bound class I MHC on cell surface (Mus musculus)
        
        Antigen peptide bound class I MHC [plasma membrane] (Mus musculus)
        
        Beta-2-microglobulin:class I MHC heavy chain Complex [plasma membrane] (Mus musculus)
        
        MHC Class I [plasma membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, alpha chain F precursor [plasma membrane] (Mus musculus)
        
        H2-Q10 [plasma membrane] (Mus musculus)
    - Antigen processing-Cross presentation (Mus musculus)
      - ER-Phagosome pathway (Mus musculus)
        
        Export of peptide loaded MHC class I complex to PM (Mus musculus)
        
        Antigen peptide bound class I MHC [plasma membrane] (Mus musculus)
        
        Beta-2-microglobulin:class I MHC heavy chain Complex [plasma membrane] (Mus musculus)
        
        MHC Class I [plasma membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, alpha chain F precursor [plasma membrane] (Mus musculus)
        
        H2-Q10 [plasma membrane] (Mus musculus)
      - Endosomal/Vacuolar pathway (Mus musculus)
        
        Translocation of peptide bound MHC class I complex to cell surface (Mus musculus)
        
        Antigen peptide bound class I MHC [plasma membrane] (Mus musculus)
        
        Beta-2-microglobulin:class I MHC heavy chain Complex [plasma membrane] (Mus musculus)
        
        MHC Class I [plasma membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, alpha chain F precursor [plasma membrane] (Mus musculus)
        
        H2-Q10 [plasma membrane] (Mus musculus)
  - Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Mus musculus)
    - TCR complex interacts with peptide antigen-presenting MHC Class I (Mus musculus)
      - Antigen peptide bound class I MHC [plasma membrane] (Mus musculus)
        
        Beta-2-microglobulin:class I MHC heavy chain Complex [plasma membrane] (Mus musculus)
        
        MHC Class I [plasma membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, alpha chain F precursor [plasma membrane] (Mus musculus)
        
        H2-Q10 [plasma membrane] (Mus musculus)
      - TCR interacting with antigen-bearing MHC Class I [plasma membrane] (Mus musculus)
        
        Antigen peptide bound class I MHC [plasma membrane] (Mus musculus)
        
        Beta-2-microglobulin:class I MHC heavy chain Complex [plasma membrane] (Mus musculus)
        
        MHC Class I [plasma membrane] (Mus musculus)
        
        Homologues of HLA class I histocompatibility antigen, alpha chain F precursor [plasma membrane] (Mus musculus)
        
        H2-Q10 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P01898 H2-Q10

Gene Names

H2-Q10

Chain

signal peptide:1-24, chain:25-325

Reference Genes

BioGPS Gene:15007 H2-Q10

CTD Gene:15007 H2-Q10

ENSEMBL:ENSMUSG00000067235 H2-Q10

KEGG Gene (Mus musculus):15007 H2-Q10

Monarch:15007 H2-Q10

NCBI Gene:15007 H2-Q10

UCSC:P01898 H2-Q10

Reference Transcript

RefSeq:NM_010391.4 H2-Q10

Other Identifiers

101898_s_at

10444841

1425137_a_at

15007

17337142

4355658

4379197

4406155

4445246

4457222

4477901

4503330

4523389

4696583

4801236

4965520

5187306

5197983

5358179

5374864

5409492

5439466

A_51_P230267

A_51_P230269

A_52_P112219

A_52_P428354

A_55_P1995092

A_55_P2037343

GE35526

ILMN_2717352

k00614_at

mMC006327

Participates

as a member of

Homologues of HLA class I histocompatibility antigen, alpha chain F precursor [plasma membrane] (Mus musculus)

Other forms of this molecule

H2-Q10 [Golgi membrane]

H2-Q10 [ER to Golgi transport vesicle membrane]

H-2 class I histocompatibility antigen, Q10 alpha chain [integral component of lumenal side of endoplasmic reticulum membrane]

H2-Q10 [early endosome membrane]

H2-Q10 [recycling endosome membrane]

H-2 class I histocompatibility antigen, Q10 alpha chain [phagocytic vesicle membrane]

H2-Q10 [plasma membrane]

H2-Q10 [phagocytic vesicle membrane]

H2-Q10 [integral component of lumenal side of endoplasmic reticulum membrane]

H2-Q10 [azurophil granule membrane]

H2-Q10 [plasma membrane]

H2-Q10 [secretory granule membrane]

Inferred From

HLA class I histocompatibility antigen, alpha chain F precursor [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_034521.1

Ensembl

ENSMUSG00000067235, ENSMUST00000174525, ENSMUSP00000066419, ENSMUST00000068291, ENSMUSP00000134163

PRO

P01898

MGI

95929

PDB

5J6H, 5J6G