Reactome | VEGFR2 [plasma membrane]

VEGFR2 [plasma membrane]

Stable Identifier

R-MMU-195382

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

P35918

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P35918 Kdr

Gene Names

Kdr, Flk-1, Flk1

Chain

signal peptide:1-19, chain:20-1345

Reference Genes

BioGPS Gene:16542 Kdr

ENSEMBL:ENSMUSG00000062960.11 Kdr

KEGG Gene (Mus musculus):16542 Kdr

Monarch:16542 Kdr

NCBI Gene:16542 Kdr

UCSC:P35918 Kdr

Reference Transcript

RefSeq:NM_010612.2 Kdr

Other Identifiers

104265_at

10530692

1449379_at

16542

17448924

4338003

4352412

4395666

4418219

4427451

4442207

4468225

4473769

4583696

4600609

4622271

4626020

4691299

4702680

4703206

4727771

4730206

4763191

4784893

4848103

4931359

5006063

5105433

5147666

5208733

5251220

5253488

5305488

5372814

5379577

5380309

5564315

5585044

5606662

A_51_P316553

A_55_P2094469

GE35648

GO:0000166

GO:0001525

GO:0001541

GO:0001569

GO:0001570

GO:0001666

GO:0001934

GO:0001936

GO:0001938

GO:0001945

GO:0002042

GO:0002053

GO:0002070

GO:0003013

GO:0003085

GO:0003157

GO:0003158

GO:0003416

GO:0003824

GO:0004672

GO:0004713

GO:0004714

GO:0005021

GO:0005178

GO:0005515

GO:0005524

GO:0005576

GO:0005634

GO:0005737

GO:0005768

GO:0005769

GO:0005783

GO:0005794

GO:0005886

GO:0006468

GO:0006914

GO:0007005

GO:0007155

GO:0007169

GO:0007204

GO:0008284

GO:0008360

GO:0008584

GO:0009410

GO:0009897

GO:0009986

GO:0010463

GO:0010595

GO:0010629

GO:0012501

GO:0015026

GO:0016020

GO:0016239

GO:0016301

GO:0016310

GO:0016477

GO:0016740

GO:0018108

GO:0019838

GO:0022414

GO:0023052

GO:0030054

GO:0030097

GO:0030154

GO:0030324

GO:0030335

GO:0030513

GO:0030949

GO:0031410

GO:0032008

GO:0034330

GO:0035162

GO:0035584

GO:0035924

GO:0036211

GO:0036324

GO:0038033

GO:0038083

GO:0038084

GO:0038085

GO:0042060

GO:0042311

GO:0042802

GO:0043025

GO:0043066

GO:0043129

GO:0043226

GO:0043235

GO:0043408

GO:0043410

GO:0043524

GO:0043536

GO:0045121

GO:0045165

GO:0045296

GO:0045446

GO:0045766

GO:0046777

GO:0048010

GO:0048170

GO:0048286

GO:0048597

GO:0048754

GO:0048812

GO:0048856

GO:0048870

GO:0050673

GO:0050679

GO:0050850

GO:0050927

GO:0051770

GO:0051894

GO:0051897

GO:0051901

GO:0055065

GO:0055074

GO:0060089

GO:0060837

GO:0061042

GO:0061154

GO:0070161

GO:0070374

GO:0071526

GO:0071944

GO:0072089

GO:0090050

GO:0090141

GO:0097443

GO:0140096

GO:1901532

GO:1903010

GO:1904881

GO:2000352

GO:2000648

GO:2001214

ILMN_2665788

mMC003369

x59397_s_at

Participates

as an input of

as a component of

Other forms of this molecule

p-Y799,Y1052,Y1172-Kdr [plasma membrane]

Kdr [plasma membrane]

Mouse Vegfr2-Human CSF1R fusion protein [plasma membrane]

phospho-p-6Y-VEGFR2 [plasma membrane]

Inferred From

VEGFR2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_034742.2

ZINC - Investigational

VGFR2_MOUSE

ZINC - World Drugs

VGFR2_MOUSE

ZINC - FDA approved

VGFR2_MOUSE

ZINC - Substances

VGFR2_MOUSE

ZINC target

P35918

Ensembl

ENSMUSP00000109144, ENSMUST00000113516, ENSMUSG00000062960

PRO

P35918

ZINC - Predictions - Purchasable

VGFR2_MOUSE

MGI

96683

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P35917 Flt4	2	p-Y1063,Y1230-Flt4 [plasma membrane] (R-MMU-9860573) Flt4 [plasma membrane] (R-MMU-9860490)	0.564	3
UniProt:P16056	7	phospho-p-Y1234,Y1235,Y1356-MET [plasma membrane] (R-MMU-6807014) phospho-p-Y1349,Y1356-MET [plasma membrane] (R-MMU-6807032) phospho-MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (R-MMU-8875181) phospho-MonoUb-K,p-Y1003,4Y-MET [plasma membrane] (R-MMU-8875180) phospho-p-Y1003,4Y-MET [plasma membrane] (R-MMU-8874689) MET [plasma membrane] (R-MMU-419603) phospho-p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (R-MMU-6806973)	0.563	3
UniProt:P08581 MET	7	p-Y1234,Y1235,Y1356-MET [plasma membrane] (R-HSA-6807014) p-Y1349,Y1356-MET [plasma membrane] (R-HSA-6807032) MonoUb-K,p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (R-HSA-8875181) MonoUb-K,p-Y1003,4Y-MET [plasma membrane] (R-HSA-8875180) p-Y1003,4Y-MET [plasma membrane] (R-HSA-8874689) MET [plasma membrane] (R-HSA-419603) p-Y1234,Y1235,Y1349,Y1356-MET [plasma membrane] (R-HSA-6806973)	0.563	3
UniProt:P09619 PDGFRB	3	p-11Y-PDGFRB [plasma membrane] (R-HSA-8864039) PDGFRB [plasma membrane] (R-HSA-186767) p-12Y-PDGFRB [plasma membrane] (R-HSA-186803)	0.524	4
UniProt:Q62077 Plcg1	10	p-Y-Plcg1 [cytosol] (R-MMU-9029083) Plcg1 [cytosol] (R-MMU-9638030) p-4Y-Plcg1 [plasma membrane] (R-MMU-9030452) phospho-p-Y771,Y783-PLCG1 [plasma membrane] (R-MMU-1169084) phospho-p-Y771,Y783,Y1254-PLCG1 [cytosol] (R-MMU-202357) PLCG1 [plasma membrane] (R-MMU-167682) P-Plcg1 [cytosol] (R-MMU-1251936) Plcg1 [plasma membrane] (R-MMU-1251925) PLCG1 [cytosol] (R-MMU-202320) phospho-p-4Y-PLCG1 [plasma membrane] (R-MMU-167679)	0.462	2