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Activated TrkA receptor complex [endosome membrane]
Stable Identifier
R-MMU-190083
Type
Complex
Species
Mus musculus
Compartment
endosome membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by NTRKs (Mus musculus)
Signaling by NTRK1 (TRKA) (Mus musculus)
Activation of TRKA receptors (Mus musculus)
TRKA activation by NGF (Mus musculus)
Activated TrkA receptor internalizes to endosomes (Mus musculus)
Activated TrkA receptor complex [endosome membrane] (Mus musculus)
Signalling to ERKs (Mus musculus)
Prolonged ERK activation events (Mus musculus)
Frs2-mediated activation (Mus musculus)
FRS2 binds to active TrkA receptor (Mus musculus)
Activated TrkA receptor complex [endosome membrane] (Mus musculus)
Active TrkA receptor:FRS2 complex [endosome membrane] (Mus musculus)
Activated TrkA receptor complex [endosome membrane] (Mus musculus)
FRS2 is phosphorylated by active TrkA receptor (Mus musculus)
Active TrkA receptor:FRS2 complex [endosome membrane] (Mus musculus)
Activated TrkA receptor complex [endosome membrane] (Mus musculus)
Active TrkA receptor:p-FRS2 complex [endosome membrane] (Mus musculus)
Activated TrkA receptor complex [endosome membrane] (Mus musculus)
p-FRS2:CRKL binds C3G (Mus musculus)
Active TrkA receptor:p-FRS2:CRKL complex [endosome membrane] (Mus musculus)
Activated TrkA receptor complex [endosome membrane] (Mus musculus)
Active TrkA receptor:p-FRS2:CRKL:RAPGEF1 [endosome membrane] (Mus musculus)
Active TrkA receptor:p-FRS2:CRKL complex [endosome membrane] (Mus musculus)
Activated TrkA receptor complex [endosome membrane] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
beta-NGF homodimer [cytosol]
(Mus musculus)
x 2
phospho-p-5Y-NTRK1-1 [endosome membrane]
(Mus musculus)
Participates
as an input of
FRS2 binds to active TrkA receptor (Mus musculus)
as an output of
Activated TrkA receptor internalizes to endosomes (Mus musculus)
as a component of
Active TrkA receptor:FRS2 complex [endosome membrane] (Mus musculus)
Active TrkA receptor:p-FRS2 complex [endosome membrane] (Mus musculus)
Active TrkA receptor:p-FRS2:CRKL complex [endosome membrane] (Mus musculus)
Inferred From
Activated TrkA receptor complex [endosome membrane]
(Homo sapiens)
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