HNF6 positively regulates Hnf1b expression

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R-MMU-186679
Type
Reaction [omitted]
Species
Mus musculus
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General
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HNF6 positively regulates Hnf1b expression

Expression of Hnf1-beta is markedly reduced in early pancreatic epithelial cells of Hnf6-deficient mice, in which formation of Ngn3+ cells is defective (Maestro et al. 2003).

Literature References
PubMed ID Title Journal Year
14570708 Hnf6 and Tcf2 (MODY5) are linked in a gene network operating in a precursor cell domain of the embryonic pancreas

Maestro, MA, Boj, SF, Luco, RF, Pierreux, CE, Cabedo, J, Servitja, JM, German, MS, Rousseau, GG, Lemaigre, FP, Ferrer, J

Hum Mol Genet 2003
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