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Anapc2 [cytosol]
Stable Identifier
R-MMU-174229
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
ANAPC2, Q8BZQ7
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Cell Cycle Checkpoints (Mus musculus)
Mitotic Spindle Checkpoint (Mus musculus)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Mus musculus)
Inactivation of APC/C via direct inhibition of the APC/C complex (Mus musculus)
Binding of the MCC complex to the APC/C complex (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
M Phase (Mus musculus)
Mitotic Metaphase and Anaphase (Mus musculus)
Mitotic Anaphase (Mus musculus)
Separation of Sister Chromatids (Mus musculus)
Association of Securin with Cdc20:APC/C complex (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
CDC20:p-APC/C:PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Degradation of multiubiquitinated Securin (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Mus musculus)
CDC20:p-APC/C:PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Regulation of mitotic cell cycle (Mus musculus)
APC/C-mediated degradation of cell cycle proteins (Mus musculus)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Mus musculus)
Association of cell cycle proteins with the APC/C:Cdh1 complex (Mus musculus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Degradation of multiubiquitinated cell cycle proteins (Mus musculus)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Mus musculus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Mus musculus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Mus musculus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Mus musculus)
APC/C:Cdc20 mediated degradation of mitotic proteins (Mus musculus)
APC/C:Cdc20 mediated degradation of Cyclin B (Mus musculus)
Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Degradation of multiubiquitinated Cyclin B (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Mus musculus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Mus musculus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Mus musculus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
APC/C:Cdc20 mediated degradation of Securin (Mus musculus)
Association of Securin with Cdc20:APC/C complex (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
CDC20:p-APC/C:PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Degradation of multiubiquitinated Securin (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Mus musculus)
CDC20:p-APC/C:PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Mus musculus)
APC-Cdc20 mediated degradation of Nek2A (Mus musculus)
Association of Nek2A with MCC:APC/C (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Nek2A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Degradation of multiubiquitinated Nek2A (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Multiubiquitinated Nek2A [cytosol] (Mus musculus)
Nek2A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Multiubiquitination of Nek2A (Mus musculus)
Multiubiquitinated Nek2A [cytosol] (Mus musculus)
Nek2A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Nek2A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Mus musculus)
Association of Cyclin A with the APC/C (Mus musculus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Degradation multiubiquitinated Cyclin A (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Mus musculus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Mus musculus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Mus musculus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Mus musculus)
Association of Cdh1 with the APC/C (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Dissociation of Cdc20 from APC/C complex (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Regulation of APC/C activators between G1/S and early anaphase (Mus musculus)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Mus musculus)
Inactivation of APC/C via direct inhibition of the APC/C complex (Mus musculus)
Binding of the MCC complex to the APC/C complex (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
S Phase (Mus musculus)
Synthesis of DNA (Mus musculus)
Switching of origins to a post-replicative state (Mus musculus)
CDK-mediated phosphorylation and removal of Cdc6 (Mus musculus)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
DNA Replication (Mus musculus)
Synthesis of DNA (Mus musculus)
Switching of origins to a post-replicative state (Mus musculus)
CDK-mediated phosphorylation and removal of Cdc6 (Mus musculus)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
Class I MHC mediated antigen processing & presentation (Mus musculus)
Antigen processing: Ubiquitination & Proteasome degradation (Mus musculus)
Interaction of E3 with substrate and E2-Ub complex (Mus musculus)
Ag-substrate:E3:E2:Ub [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
APC/C E3 ligase complex [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
APC/C E3 ligase complex [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Polyubiquitination of substrate (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
APC/C E3 ligase complex [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
E3:K48-polyubiquitinated substrate [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
APC/C E3 ligase complex [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
E3:Ub:substrate [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
APC/C E3 ligase complex [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Release of E3 from polyubiquitinated substrate (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
APC/C E3 ligase complex [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
E3:K48-polyubiquitinated substrate [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
APC/C E3 ligase complex [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
Transfer of Ub from E2 to substrate and release of E2 (Mus musculus)
Ag-substrate:E3:E2:Ub [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
APC/C E3 ligase complex [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
APC/C E3 ligase complex [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
E3:Ub:substrate [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
APC/C E3 ligase complex [cytosol] (Mus musculus)
Anapc2 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q8BZQ7
Gene Names
Anapc2
Reference Genes
BioGPS Gene:99152 Anapc2
ENSEMBL:ENSMUSG00000026965
ENSEMBL:ENSMUSG00000026965.13 Anapc2
KEGG Gene (Mus musculus):99152 Anapc2
Monarch:99152 Anapc2
NCBI Gene:99152 Anapc2
UCSC:Q8BZQ7 Anapc2
Reference Transcript
RefSeq:NM_175300.4 Anapc2
Other Identifiers
10338383
10338528
10338974
10339216
10339530
10339692
10339988
10340427
10341316
10341861
10342641
10343019
10343221
10343299
10344279
10469965
1415707_at
17367892
4342954
4429226
4562667
4581670
4625113
4668128
4843424
4918982
4946718
5079151
5138467
5159064
5259982
5324694
5401488
5446670
5460792
5580442
95128_at
99152
A_51_P468398
A_52_P237414
A_52_P659417
A_55_P1986660
A_55_P2803974
GE1544473
GO:0000278
GO:0005634
GO:0005680
GO:0006511
GO:0007049
GO:0007059
GO:0007091
GO:0007399
GO:0010629
GO:0016567
GO:0023052
GO:0030154
GO:0030163
GO:0031625
GO:0031915
GO:0034330
GO:0036211
GO:0043226
GO:0045773
GO:0048856
GO:0050775
GO:0051301
GO:0070979
GO:0090129
ILMN_2614189
ILMN_2901312
mMC007011
Participates
as a component of
APC/C E3 ligase complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Other forms of this molecule
Anapc2 [nucleoplasm]
Inferred From
ANAPC2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_780509.2
Ensembl
ENSMUST00000028341
,
ENSMUSG00000026965
,
ENSMUSP00000028341
PRO
Q8BZQ7
MGI
2139135
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