Reactome | RAF1 [cytosol]

RAF1 [cytosol]

Stable Identifier

R-MMU-167205

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

Q99N57

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q99N57

Reference Genes

BioGPS Gene:110157

dbSNP Gene:110157

ENSEMBL:ENSMUSG00000000441

KEGG Gene (Mus musculus):110157

Monarch:110157

NCBI Gene:110157

UCSC:Q99N57

Reference Transcript

Other Identifiers

10547034

110157

1416078_s_at

1425419_a_at

17469894

4364488

4382407

4552942

4574845

4598310

4599262

4629137

4853093

4881848

4949521

4961361

5098067

5133730

5139630

5157830

5223962

5241129

5267873

5307983

5367810

5563343

5584314

5599575

94264_at

A0A0N4SWH5

A_51_P404204

A_52_P214058

A_52_P412600

A_55_P1973643

AAH15273

AAH92040

AB057655

AB057663

AK141745

BAB39743

BAB39748

BAE24820

BC015273

BC092040

CCDS20441

ENSMUSG00000000441

ENSMUSP00000000451

ENSMUSP00000108571

ENSMUST00000000451

ENSMUST00000112949

EntrezGene:110157

GE125263

GO:0000165

GO:0000166

GO:0000186

GO:0001666

GO:0001678

GO:0001934

GO:0002376

GO:0003674

GO:0004672

GO:0004674

GO:0004709

GO:0005515

GO:0005524

GO:0005575

GO:0005622

GO:0005623

GO:0005634

GO:0005654

GO:0005737

GO:0005739

GO:0005794

GO:0005829

GO:0005886

GO:0006464

GO:0006468

GO:0006810

GO:0006950

GO:0007010

GO:0007165

GO:0007190

GO:0007267

GO:0007507

GO:0008150

GO:0008179

GO:0008219

GO:0008283

GO:0008285

GO:0009058

GO:0010856

GO:0016020

GO:0016301

GO:0016310

GO:0016607

GO:0016740

GO:0017016

GO:0019899

GO:0022607

GO:0030154

GO:0030234

GO:0030878

GO:0031143

GO:0031333

GO:0031434

GO:0033138

GO:0034641

GO:0035019

GO:0035556

GO:0035773

GO:0035994

GO:0042592

GO:0042802

GO:0043066

GO:0043167

GO:0043226

GO:0045104

GO:0045944

GO:0046872

GO:0046982

GO:0048011

GO:0048538

GO:0048856

GO:0060324

GO:0065003

GO:0071550

GO:1902042

ILMN_2747229

IPR000719

IPR001245

IPR002219

IPR003116

IPR008271

IPR011009

IPR017441

IPR020454

IPR029071

MGI:97847

mMC010690

Msa.24413.0_s_at

Msa.6334.0_s_at

NM_001356334

NM_029780

NP_001343263

NP_084056

PF00130

PF02196

PF07714

PR00008

Raf1

Raf1-201

Raf1-202

SM00109

SM00220

SM00455

uc009dix.1

uc009diy.1

UPI0000027F74

X55432

XM_006505363

XM_006505364

XM_006505365

XP_006505427

XP_006505428

Participant Of

input

hasComponent

Other forms of this molecule

phospho-p-S338,Y340,Y341-RAF1 [cytosol]

phospho-p-S338-RAF1 [cytosol]

phospho-p-S259,S621-RAF1 [cytosol]

phospho-hyperphosphorylated RAF1 [plasma membrane]

phospho-p-S621-RAF1 [plasma membrane]

phospho-p-Y341,T491,S494,S621 RAF1 [plasma membrane]

phospho-p-S621-RAF1 [cytosol]

phospho-p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane]

phospho-p-S338,Y341,T491,S494,S621 RAF1 [cytosol]

Inferred From

RAF1 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_006505426.1, XP_006505428.1, NP_084056.1, XP_006505427.1

BRENDA (Mus musculus)

2.7.11.1

PRO

Q99N57

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P35438 Grin1	1	Grin1 [plasma membrane] (R-MMU-3928395)	0.643	4
UniProt:P28028	6	phospho-p-S365,S445,S729 BRAF [cytosol] (R-MMU-5672667) BRAF [cytosol] (R-MMU-167224) phospho-hyperphosphorylated BRAF [plasma membrane] (R-MMU-5675199) phospho-p-S445,T599,S602,S729 BRAF [plasma membrane] (R-MMU-5672679) phospho-p-S445,S729-BRAF [cytosol] (R-MMU-5672673) phospho-p-S445,T599,S602,S729 BRAF [cytosol] (R-MMU-5672676)	0.589	2
UniProt:Q8CFI0 NED4L			0.524	2
UniProt:Q9Z2S7-3 TSC22D3			0.524	2
UniProt:P01111 NRAS	8	G13D NRAS [plasma membrane] (R-HSA-6802363) NRAS [tertiary granule membrane] (R-HSA-6800190) Q61R NRAS [plasma membrane] (R-HSA-6802461) Q61L NRAS [plasma membrane] (R-HSA-6802455) G12S NRAS [plasma membrane] (R-HSA-6802347) Q61K NRAS [plasma membrane] (R-HSA-6802446) G12D NRAS [plasma membrane] (R-HSA-6802339) NRAS [plasma membrane] (R-HSA-62725)	0.499	2
UniProt:P15056 BRAF	32	p-BRAF-MACF1 fusion [cytosol] (R-HSA-6802536) BRAF-MACF1fusion [cytosol] (R-HSA-6802402) D594N BRAF [cytosol] (R-HSA-6802299) G596R BRAF [cytosol] (R-HSA-6802385) D594V BRAF [cytosol] (R-HSA-6802305) G466E BRAF [cytosol] (R-HSA-6802374) D594G BRAF [cytosol] (R-HSA-6802295) F595L BRAF [cytosol] (R-HSA-6802316) L597V BRAF [cytosol] (R-HSA-6802397) G464E BRAF [cytosol] (R-HSA-6802369) E586K BRAF [cytosol] (R-HSA-6802308) V600K BRAF [cytosol] (R-HSA-6802502) p-L597V BRAF [plasma membrane] (R-HSA-8936647) p-G464E BRAF [plasma membrane] (R-HSA-8936645) p-F595L BRAF [plasma membrane] (R-HSA-8936641) p-E586K BRAF [plasma membrane] (R-HSA-8936639) p-V600K BRAF [plasma membrane] (R-HSA-8936651) BRAF 599dupT [cytosol] (R-HSA-6802281) G469A BRAF [cytosol] (R-HSA-6802381) V600E BRAF [cytosol] (R-HSA-6802498) V600E BRAF V169_M438del [cytosol] (R-HSA-6802489) V600E BRAF V47_D380del [cytosol] (R-HSA-6802491) V600E BRAF V47_M438del [cytosol] (R-HSA-6802495) V600E BRAF V169_D380del [cytosol] (R-HSA-6802486) p-S445,S729-BRAF [plasma membrane] (R-HSA-8933622) p-S,T-BRAF [cytosol] (R-HSA-169856) BRAF [cytosol] (R-HSA-167224) p-S365,S445,S729 BRAF [cytosol] (R-HSA-5672667) hyperphosphorylated BRAF [plasma membrane] (R-HSA-5675199) p-S445,T599,S602,S729 BRAF [plasma membrane] (R-HSA-5672679) p-S445,S729-BRAF [cytosol] (R-HSA-5672673) p-S445,T599,S602,S729 BRAF [cytosol] (R-HSA-5672676)	0.499	3