Reactome | Masp2 [extracellular region]

Masp2 [extracellular region]

Stable Identifier

R-MMU-166689

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

extracellular region

Synonyms

MASP2-1, Q91WP0

Locations in the PathwayBrowser

Expand all

Immune System (Mus musculus)

- Innate Immune System (Mus musculus)
  - Complement cascade (Mus musculus)
    - Initial triggering of complement (Mus musculus)
      - Conversion of C2 into C2a and C2b (Mus musculus)
        
        C4 activators [plasma membrane] (Mus musculus)
        
        CL-LK:MASP1 dimer:MASP2 dimer:Bacterial mannose surface pattern:4xCa2+ [plasma membrane] (Mus musculus)
        
        CL-LK:MASP1 dimer:MASP2 dimer [extracellular region] (Mus musculus)
        
        MASP2-1 dimer [extracellular region] (Mus musculus)
        
        Masp2 [extracellular region] (Mus musculus)
      - Conversion of C4 into C4a and C4b (Mus musculus)
        
        C4 activators [plasma membrane] (Mus musculus)
        
        CL-LK:MASP1 dimer:MASP2 dimer:Bacterial mannose surface pattern:4xCa2+ [plasma membrane] (Mus musculus)
        
        CL-LK:MASP1 dimer:MASP2 dimer [extracellular region] (Mus musculus)
        
        MASP2-1 dimer [extracellular region] (Mus musculus)
        
        Masp2 [extracellular region] (Mus musculus)
      - Creation of C4 and C2 activators (Mus musculus)
        
        Lectin pathway of complement activation (Mus musculus)
        
        Activation of MASPs (Mus musculus)
        
        MBL2,FCN:MASPs:carbohydrate patterns [plasma membrane] (Mus musculus)
        
        FCN1 ligands:FCN1 dodecamer:MASP1 dimer:MASP2-1 dimer:4xCa2+ [plasma membrane] (Mus musculus)
        
        FCN1 dodecamer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Mus musculus)
        
        MASP2-1 dimer [extracellular region] (Mus musculus)
        
        Masp2 [extracellular region] (Mus musculus)
        
        FCN2 ligands:FCN2 dodecamer:MASP1 dimer:MASP2-1 dimer:4xCa2+ [plasma membrane] (Mus musculus)
        
        FCN2 dodecamer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Mus musculus)
        
        MASP2-1 dimer [extracellular region] (Mus musculus)
        
        Masp2 [extracellular region] (Mus musculus)
        
        CL-LK binds carbohydrates on target cell surface (Mus musculus)
        
        CL-LK:MASP1 dimer:MASP2 dimer [extracellular region] (Mus musculus)
        
        MASP2-1 dimer [extracellular region] (Mus musculus)
        
        Masp2 [extracellular region] (Mus musculus)
        
        CL-LK:MASP1 dimer:MASP2 dimer:Bacterial mannose surface pattern:4xCa2+ [plasma membrane] (Mus musculus)
        
        CL-LK:MASP1 dimer:MASP2 dimer [extracellular region] (Mus musculus)
        
        MASP2-1 dimer [extracellular region] (Mus musculus)
        
        Masp2 [extracellular region] (Mus musculus)
        
        Ficolins bind to repetitive carbohydrate structures on the target cell surface (Mus musculus)
        
        Ficolin-1 binds to molecular patterns on the target cell surface (Mus musculus)
        
        FCN1 dodecamer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Mus musculus)
        
        MASP2-1 dimer [extracellular region] (Mus musculus)
        
        Masp2 [extracellular region] (Mus musculus)
        
        FCN1 ligands:FCN1 dodecamer:MASP1 dimer:MASP2-1 dimer:4xCa2+ [plasma membrane] (Mus musculus)
        
        FCN1 dodecamer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Mus musculus)
        
        MASP2-1 dimer [extracellular region] (Mus musculus)
        
        Masp2 [extracellular region] (Mus musculus)
        
        Ficolin-2 binds to molecular patterns on the target cell surface (Mus musculus)
        
        FCN2 dodecamer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Mus musculus)
        
        MASP2-1 dimer [extracellular region] (Mus musculus)
        
        Masp2 [extracellular region] (Mus musculus)
        
        FCN2 ligands:FCN2 dodecamer:MASP1 dimer:MASP2-1 dimer:4xCa2+ [plasma membrane] (Mus musculus)
        
        FCN2 dodecamer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Mus musculus)
        
        MASP2-1 dimer [extracellular region] (Mus musculus)
        
        Masp2 [extracellular region] (Mus musculus)

External Reference Information

External Reference

UniProt:Q91WP0

Gene Names

Masp2

Reference Genes

BioGPS Gene:17175 Masp2

ENSEMBL:ENSMUSG00000028979

KEGG Gene (Mus musculus):17175 Masp2

Monarch:17175 Masp2

NCBI Gene:17175 Masp2

UCSC:Q91WP0 Masp2

Reference Transcript

Other Identifiers

10510399

131693_at

1420524_a_at

1451759_at

17175

17421704

4314578

4353515

4401317

4434511

4638172

4742010

4750471

4793009

4793828

4806240

5187668

5341526

5378966

5441757

5442339

98481_at

A_51_P448464

A_51_P448466

A_52_P569276

A_55_P1990500

A_55_P1990505

A_55_P2185504

GE42641

GO:0001855

GO:0001867

GO:0002376

GO:0003674

GO:0004252

GO:0005509

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0006508

GO:0006950

GO:0006958

GO:0008150

GO:0008233

GO:0008236

GO:0016787

GO:0042802

GO:0043167

GO:0045087

GO:0046872

GO:0048306

ILMN_1216142

ILMN_1260242

ILMN_2487104

ILMN_2487105

ILMN_3027989

ILMN_3101073

Msa.6555.0_s_at

mMC016135

Participates

as a component of

MASP2-1 dimer [extracellular region] (Mus musculus)

Other forms of this molecule

Masp2 [extracellular region]

Inferred From

MASP2-1 [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_034897.1, NP_001003893.1

Ensembl

ENSMUST00000052060, ENSMUSP00000049729, ENSMUST00000105701, ENSMUSP00000101326, ENSMUSG00000028979

PRO

Q91WP0

GlyGen

Q91WP0

MGI

1330832

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